… Median tumor purity (0.53 (IQR 0.38–0.67) was estimated on the obtained sequencing data
and was not significantly different between biopsy sites. Based on a previously described …

… However, retinoblastoma cases exist where mutations in RB1 have not been detected.
We used whole-genome sequencing to investigate the landscape of mutations in a cohort of …

… to generate enough DNA for reliable whole-genome sequencing (WGS). The disadvantages
… reveals intriguing differences between sites. The UV mutational signature is subtly different …

… [8], we performed whole-genome sequencing to characterize novel mutation-… difference
between small and large deletor subgroups with respect to gleason score suggests differences …

… We present mutational signature analyses of 12,222 whole-genome–sequenced cancers
collected prospectively via the UK National Health Service (NHS) for the 100,000 Genomes …

… We therefore leveraged the comprehensive resolution of whole-genome sequencing to
assess 51 tumor samples from 49 patients with CAR-19–treated large B-cell lymphoma. We …

… whole-genome sequencing analysis of 2,023 tumours. We provide the most detailed high-resolution
map to date of somatic mutations in … We compared genomic differences between the …

… We examined a wide selection of genomic features to search for differences between IBC
and conventional breast cancer. These include (i) somatic and germline single-nucleotide …

… Whole-genome sequencing and Sanger sequencing verification The overall somatic mutational
landscape of the different … displayed a mutation rate of around five somatic mutations per …

… whole-genome sequencing (WGS) of 150 ATL cases to reveal the overarching landscape of
genetic … In the non-coding genome, we identified recurrent mutations in regulatory elements, …