… of the canonical Wnt pathway in animal bone regeneration models. … the roles of Wnt and
β-catenin in fracture healing, but also the … pathway is by far the most extensively studied in bone …

… bone remodelling and fracture healing and are emerging as … was so far attributed to the Wnt
or Hippo signalling pathway … and renewal of MSCs, non-canonical Wnt signalling has been …

… The canonical Wnt/β-catenin signaling enhances bone healing through accelerating MSC
differentiation into osteoblasts and chondrocytes, which form cartilage. In contrast, Notch …

… Even after a bone is matured, the process of bone regeneration continues through periodic
… Recently, owing to its non-coding variants, the TCF4 gene has become by far the strongest …

… maintain and regenerate bone during homeostasis and repair. … signalling pathways during
bone repair are described, as … The WNT pathway is required downstream of HH signalling to …

… Therefore, in this review, we discuss which biomaterials elicit or influence pathways relevant
for bone regeneration … development of novel, more effective bone regenerative therapies. …

… Wnt pathway in bone repair and regeneration—What do we know so far. Front Cell Dev
Biol 2019;6:170; doi: 10.3389/fcell.2018.00170 Crossref, Medline, Google Scholar …

… In this review, we address the so far largely unknown role … stimulate cooperative signaling
and optimize bone repair is needed. … Wnt signaling and directs osteogenesis to where bone is …

… bone formation and improved fracture healing (82–84), confirming the inhibitory effect of …
Thus far, consistent results have demonstrated the expression of TLR1-6 in adipose- and …

… -signature genes and activation of canonical Wnt signaling that induced the transition of
Cxcl12-… nerves play an important role in bone regeneration and repair. Rodent studies show that …