[HTML][HTML] Maternal-fetal interplay in Zika virus infection and adverse perinatal outcomes

FME Teixeira, AJ Pietrobon, LM Oliveira… - Frontiers in …, 2020 - frontiersin.org
neonatal plasmacytoid DCs (86). Additionally, macrophages derived from cord blood monocytes
show reduced IL-6 … reservoirs for the virus without significant immunological activation, …

[HTML][HTML] Maternal immune response to ZIKV triggers high-inflammatory profile in congenital Zika syndrome

EMS Fialho, EM Veras, CM de Jesus, R Khouri… - Viruses, 2023 - mdpi.com
… to Zika virus infection [14]. This condition may favor the infection’s immunopathology by
providing a more significant replication site and viral … + children who had monocytes with a more …

[HTML][HTML] Hide and seek: the interplay between Zika virus and the host immune response

LJ Lee, TV Komarasamy, NAA Adnan… - Frontiers in …, 2021 - frontiersin.org
… -classic monocytes, and NK cells) as early targets of the virus and … seen in pregnant women
carrying babies with brain anomalies (… , IL-6, IL-8 and VEGF in amniotic fluid of ZIKV-infected

[HTML][HTML] Zika virus infects human placental mast cells and the HMC-1 cell line, and triggers degranulation, cytokine release and ultrastructural changes

K Rabelo, AJS Gonçalves, LJ Souza, AP Sales… - Cells, 2020 - mdpi.com
… At 38 weeks of gestation, her baby girl was born by cesarean … from infected mothers,
extensive reactivity was seen in not … of mast cells, as well as monocytes, CD4+ and CD8+ T cells, …

Zika virus infection of first trimester trophoblast cells affects cell migration, metabolism and immune homeostasis control

D Vota, M Torti, D Paparini… - Journal of Cellular …, 2021 - Wiley Online Library
… observed in newborns from pregnant women infected with ZIKV, … increase of proinflammatory
cytokines. On the other hand, … in monocytes cultured with conditioned media from ZIKV …

Gas6 drives Zika virus-induced neurological complications in humans and congenital syndrome in immunocompetent mice

JL Silva-Filho, LG de Oliveira, L Monteiro… - Brain, behavior, and …, 2021 - Elsevier
… a significant upregulation of Gas6 production in monocytes, … Samples of 8 ZIKV-infected
pregnant women and 6 infants … variety of cytokines with key roles in the antiviral response, Gas6 …

[HTML][HTML] Maternal Th17 profile after Zika virus infection is involved in congenital Zika syndrome development in children

EMS Fialho, EM Veras, CM Jesus, LN Gomes, R Khouri… - Viruses, 2023 - mdpi.com
… This outbreak raised significant concerns about the … of monocytes with different strains of the
ZIKV show the virus’s … Beyond the effects of cytokines during pregnancy, infants exposed to …

[HTML][HTML] Concomitant pyroptotic and apoptotic cell death triggered in macrophages infected by Zika virus

C Wen, Y Yu, C Gao, X Qi, CJ Cardona, Z Xing - PLos One, 2022 - journals.plos.org
… , leading to spontaneous abortions and severe neonatal birth … of viral infections and host
defense, in which monocytes and … In addition to cytokine and chemokine release, monocytes/…

[HTML][HTML] Pathogenesis and manifestations of Zika virus-associated ocular diseases

BA Labib, DGI Chigbu - Tropical Medicine and Infectious Disease, 2022 - mdpi.com
… (ZIKV) is mosquito-borne flavivirus that caused a significant … , whereas microcephaly in
newborn infants was associated with … infected monocytes become activated to secrete cytokines

Zika virus: Antiviral immune response, inflammation, and cardiotonic steroids as antiviral agents

JM de Sales-Neto, DCM Carvalho… - International …, 2024 - Elsevier
… , monocytes, upon infected by ZIKV in the peripheral blood, express several cytokines, … ,
particularly congenital microcephaly, in newborns, prompting several national agencies to issue …