Comparison of Vascular Morphometry in Jawbones and Long Bones: Micro‐CT Study in a Rat Model Treated with Zoledronic Acid

JY Wang, RQ Yu, L Huo, NJ Rao… - BioMed Research …, 2021 - Wiley Online Library
… on vascularization and the site-specific response of neovessel formation in … with zoledronic
acid administration and maxillary molar extraction, and they found a decreased blood vessel

[HTML][HTML] Expression of angiogenic markers in jawbones and femur in a rat model treated with zoledronic acid

JW Li, JY Wang, RQ Yu, L Huo, LW Zheng - BMC Research Notes, 2022 - Springer
… , found that zoledronic acid treatment had a site-specific effect … A tendency of decreased
vessel density and vessel number … of ZA did not affect blood vessel formation. This was also …

Zoledronic acid modulates osteoclast apoptosis through activation of the NF-κB signaling pathway in ovariectomized rats

YT Cheng, J Liao, Q Zhou, H Huo… - Experimental …, 2021 - journals.sagepub.com
… showed that ovariectomized induced the protein levels of … osteoclasts, whereas zoledronic
acid inhibited these inductions. … -resorptive drugs induce rapid dose-dependent decreases in …

[HTML][HTML] Delayed alveolar bone repair and osteonecrosis associated with Zoledronic Acid therapy in rats: macroscopic, microscopic and molecular analysis

GZ Ferreira, EV Zen Filho, IRF Rubira-Bullen… - Journal of Applied Oral …, 2020 - SciELO Brasil
Zoledronic acid induces site-specific structural changes and decreases vascular area in the
alveolar … Zoledronic acid increases the circulating soluble RANKL level in mice, with a further …

[HTML][HTML] Impact of whole body vibration and zoledronic acid on femoral structure after ovariectomy: morphological evaluation

NM Kostyshyn, I Świetlicka, E Tomaszewska… - Journal of Clinical …, 2022 - mdpi.com
… Vibration causes intracellular fluid fluctuations in osteocytes … ovarian bursa to ligate the
ovarian artery and vein, then the … The BV/TV ratio decreased after 16 weeks for both treatments…

[PDF][PDF] Towards novel measurements of remodeling activity in cortical bone: implications for osteoporosis and related pharmaceutical treatments

LL Loundagin, DML Cooper - Eur. Cell Mater, 2022 - ecmjournal.org
… , disuse and glucocorticoid-induced osteoporosis as well as … is formed or resorbed in a
site-specific manner. If so, local … receiving teriparatide or zoledronic acid in the SHOTZ trial. J …

[HTML][HTML] Zoledronate loaded polylactic acid/polycaprolactone/hydroxyapatite scaffold accelerates regeneration and led to enhance structural performance and …

A Oryan, S Hassanajili, S Sahvieh - Iranian Journal of Veterinary …, 2023 - ncbi.nlm.nih.gov
… qRT-PCR was also done to define the osteoinductivity and angiogenic induction capacity
of this scaffold. Forty rats were selected and randomly divided into four groups: the control …

[HTML][HTML] Tetrahedral framework nucleic acid carrying angiogenic peptide prevents bisphosphonate-related osteonecrosis of the jaw by promoting angiogenesis

D Zhao, D Xiao, M Liu, J Li, S Peng, Q He… - International Journal of …, 2022 - nature.com
reduce the occurrence of BRONJ. As for angiogenesis, the … , induction endothelial cell
migration, and formation lumen-like … , other rats received intravenous Zoledronic acid (ZA) (125 μg·…

[HTML][HTML] Preventive effect of teriparatide on medication-related osteonecrosis of the jaw in rats

KM Park, N Lee, J Kim, HS Kim, W Park - Scientific reports, 2023 - nature.com
… extraction helped reduce the occurrence of MRONJ in rats treated with zoledronic acid, …
Therefore, in this study, MRONJ was induced by extraction after inducing periodontitis through …

Small extracellular vesicles derived from adipose tissue prevent bisphosphonate-related osteonecrosis of the jaw by promoting angiogenesis

J Huang, L Wang, W Tian - International Journal of Nanomedicine, 2021 - Taylor & Francis
… (C) Open area without epithelium coverage. Open area was significantly decreased by sEV-AT
… The effects of sEV-AT on altered micro-environment of maxillofacial bone induced by Zol …