… 2-related factor 2 (NRF2) is to activate the cellular anti- oxidant response by inducing the …
effect of N-acetyl-L-cysteine (NAC), as an antioxidant drug, on NRF2 Gene Expression in …

… antioxidant response [1]. Under conditions of oxidative stress, NRF2 translocates to the nucleus
and binds to antioxidant … mediated acetylation of NRF2 causes dissociation of NRF2 from …

… In conclusion, these results suggested that SFN activates Nrf2 by inhibiting HDACs and
increasing histone acetylation levels, which may play a crucial role in preventing Ang II-induced …

… Nfe2l2/Keap1 genes, acetylation of lysine residues in NRF2 and Nrf2, interaction with …
NRF2 to antioxidant response element (ARE) sequences in gene promoters activates antioxidant …

… antioxidant protein (NQO1, GCLM, HO-1 and GCLC) and phase II detoxification enzyme by
interacting with the antioxidant response element ARE (antioxidant response … the acetylation …

… NRF2 and ATF4 have been reported to concur in enhancing GSH levels and mounting the
antioxidant response… to switch from the adaptive response to pro-apoptotic signaling. ATF4 …

… acetylation modulated by TSA led to abnormal response in terms … Nrf2 is stabilized and
translocates to the nucleus (32 ), and in the nucleus, Nrf2 combines with the antioxidant response …

… Two of the main players in the molecular and cellular response to OS are NRF2, the
transcription nuclear factor erythroid 2-related factor 2, and its principal negative regulator, KEAP1, …

… the antioxidant response element (ARE), which allows Nrf2 the … responses by inhibiting
CBP-dependent acetylation of Nrf2 at … At Point 29, we can see the reversibility of Nrf2 acetylation …

… of the antioxidant N-acetyl-l-cysteine (NAC) or aminoguanidine (AG) in the media. Both NAC
and AG partially prevented decreases in insulin mRNA, insulin gene promoter activity, DNA …