… acute kidney injury (AKI), renal tubular cells may stimulate fibroblasts in a paracrine fashion
leading to interstitial fibrosis… to activate fibroblasts for renal fibrosis. After ischemic AKI in mice…

… with acute kidney injury (AKI) who survive the acute stage are at notable risk for chronic
kidney disease (… in several diseases, such as renal fibrosis. Previous research has shown that …

… The final pathological alteration of CKD is renal fibrosis, but the specific mechanism
underlying renal fibrosis is not fully understood. To date, increasing evidence has supported the …

… , including inflammation, repair, and fibrosis. Current evidence suggests that … kidney disease
(CKD), decrease discard of AKI kidneys, differentiate between kidney dysfunction and injury, …

… fibrosis. Several systems, molecules and responses involved in the pathogenesis of the
pathological fibrosis of chronic kidney disease … drive fibrosis, having a great negative kidney and …

… Acute kidney injury (AKI) and chronic kidney diseases are associated with high mortality
and morbidity. Although the underlying mechanisms determining the transition from …

… fibrosis. In conclusion, CypA promotes inflammation and acute kidney injury in renal IRI, but
… not contribute to inflammation or interstitial fibrosis in a model of progressive kidney fibrosis. …

… of macrophage accumulation after kidney injury. In addition, dynamic … changes in handling
kidney inflammation and fibrosis. … during acute kidney injury (AKI) and chronic kidney disease (…

… Even in patients with functional loss, functional recovery might conceal unresolved kidney
damage that can lead to fibrosis and eventually to CKD. For example, in a mouse model of …

… these changes could trigger early hallmarks of fibrosis, … damage not only accelerated
ageing mechanisms but also facilitated the development of early fibrotic changes in the kidney…