Devices and formulations: General introduction and wet aerosol delivery systems

AH de Boer, K Thalberg - Inhaled Medicines, 2021 - Elsevier
delivery has been developed for these principles to increase the efficiency of lung deposition.
This opens the way for the administration of new and expensive biopharmaceuticals, but …

State-of-the-art review of the application and development of various methods of aerosol therapy

M Matuszak, M Ochowiak, S Włodarczak… - International Journal of …, 2022 - Elsevier
aerosol therapy, it is necessary to become familiar with the basic principles and applications
of aerosol … properties of the sprayed system, the design of the medical inhaler and its correct …

Effect of functional principle, delivery technique, and connection used on aerosol delivery from different nebulizers: An in-vitro study

NEE Sayed, MA Abdelrahman… - Pulmonary Pharmacology …, 2021 - Elsevier
principle into jet, ultrasonic and vibrating mesh nebulizers with intermittent or continuous
aerosol delivery … The nebulizer types and designs are many with different properties and may …

[HTML][HTML] Human lung cell models to study aerosol delivery–Considerations for model design and development

B Rothen-Rutishauser, M Gibb, R He… - European Journal of …, 2023 - Elsevier
… of aerosol exposure … design of a model as well as how the aerosol properties determine
the interfacial properties with the respiratory wall. The most important aspects on how to design

Recent advances in aerosol devices for the delivery of inhaled medications

A Ari, JB Fink - Expert Opinion on Drug Delivery, 2020 - Taylor & Francis
… been an increased interest in the development of aerosol delivery devices over the years.
Technical innovations have advanced device design, novel features such as breath actuation, …

Aerosol therapy in adult critically ill patients: a consensus statement regarding aerosol administration strategies during various modes of respiratory support

J Li, K Liu, S Lyu, G Jing, B Dai, R Dhand, HL Lin… - Annals of intensive …, 2023 - Springer
… We offer a multinational expert consensus that provides guidance on the optimal aerosol
delivery … An alternative is to employ HMEs designed to allow aerosol delivery (HME-ADs) by …

CFD guided optimization of nose-to-lung aerosol delivery in adults: effects of inhalation waveforms and synchronized aerosol delivery

R Dutta, B Spence, X Wei, S Dhapare, M Hindle… - Pharmaceutical …, 2020 - Springer
aerosol delivery in an adult upper airway model using computational fluid dynamics (CFD)
simulations in order to guide subsequent human subject aerosol delivery … nebulizer design

[HTML][HTML] Aerosol delivery via noninvasive ventilation: role of models and bioanalysis

H Saeed, HS Harb, YM Madney… - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
… nebulizer designs on the aerosol delivery from each designdesigns of jet nebulizers (3
designs) have a significant effect on the aerosol delivery, while all tested designs (3 designs) of …

[HTML][HTML] A path to successful patient outcomes through aerosol drug delivery to children: A narrative review

A Ari - Annals of translational medicine, 2021 - ncbi.nlm.nih.gov
… the current knowledge on aerosol delivery devices used in … Many aerosol delivery devices
were developed more than 50 … of current aerosol delivery devices were designed for adults, it …

A path forward in the development of new aerosol drug delivery devices for pediatrics

JA O'Neil, LA Villasmil-Urdaneta - Respiratory Medicine, 2023 - Elsevier
… These losses can contribute to low dosing efficiency and significant variability in dosing,
making the device-facemask design integration important for maximizing aerosol delivery. As …