Evidence-based pharmacotherapies for alcohol use disorder: clinical pearls

J Fairbanks, A Umbreit, BP Kolla, VM Karpyak… - Mayo Clinic …, 2020 - Elsevier
… to heavy drinking and total alcohol consumption. The FDA approved extended-release
injectable naltrexone (Vivitrol) to treat people with alcohol dependence in 2006. In October 2010, …

Efficacy of gabapentin for the treatment of alcohol use disorder in patients with alcohol withdrawal symptoms: a randomized clinical trial

RF Anton, P Latham, K Voronin, S Book… - JAMA internal …, 2020 - jamanetwork.com
… Combined pharmacotherapies and behavioral interventions for alcohol dependence: the …
for AUD, including alcohol withdrawal, as determined by Structured Clinical Interview for DSM-…

The role of the central amygdala in alcohol dependence

M Roberto, D Kirson, S Khom - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
… -induced adaptations in CeA neurons and their behavioral implications in alcohol-dependent
and/or alcohol-withdrawn organisms. These ongoing studies may elucidate the mechanism…

[HTML][HTML] Alcohol's unique effects on cognition in women: A 2020 (re) view to envision future research and treatment

R Fama, AP Le Berre, EV Sullivan - Alcohol research: current …, 2020 - ncbi.nlm.nih.gov
… the disease—for example, “alcohol abuse” and “alcohol dependence” in the fourth edition
of … of alcohol misuse will continue to have both theoretical and clinical implications, steering …

Effect of cognitive bias modification on early relapse among adults undergoing inpatient alcohol withdrawal treatment: a randomized clinical trial

V Manning, JBB Garfield, PK Staiger, DI Lubman… - JAMA …, 2021 - jamanetwork.com
… The findings of this clinical trial support the efficacy of CBM for treatment of alcohol use
disorder. Being safe and easy to implement, requiring only a computer and joystick, and needing …

Alcohol use disorders and the brain

R Rao, A Topiwala - Addiction, 2020 - Wiley Online Library
… people with alcohol dependence [45]; 80% of WE cases are only diagnosed at post-mortem. …
-long implications for their ability to live independently. Alcohol dependence accompanied …

Gut-liver axis: Pathophysiological concepts and clinical implications

H Tilg, TE Adolph, M Trauner - Cell metabolism, 2022 - cell.com
Clinical evidence describes perturbation of the gut-liver crosstalk in non-alcoholic fatty
liver disease, alcoholic liver disease, and primary sclerosing cholangitis. In liver cirrhosis, a …

Alcohol addiction, gut microbiota, and alcoholism treatment: a review

SC Wang, YC Chen, SJ Chen, CH Lee… - International journal of …, 2020 - mdpi.com
… to risk for alcoholism [57]. Genetic variations in different individuals affect the risk of … alcohol
dependence. For example, the allele ADH1 B*3 induces a more rapid metabolism of alcohol

Diagnosis and treatment of alcohol-associated liver disease: a review

AK Singal, P Mathurin - Jama, 2021 - jamanetwork.com
… a Patients with severe alcoholic hepatitis whose condition has not responded to …
clinical trials in patients with alcoholic hepatitis: recommendation from the NIAAA Alcoholic

Incidence and progression of alcohol-associated liver disease after medical therapy for alcohol use disorder

AGL Vannier, JES Shay, V Fomin, SJ Patel… - JAMA Network …, 2022 - jamanetwork.com
alcohol abuse and alcohol dependence), compared with patients who received any other
medication for AUD. Although the preponderance of evidence suggests that acamprosate may …