Synthesis of amphiphilic Janus dendrimer and its application in improvement of hydrophobic drugs solubility in aqueous media

F Najafi, M Salami-Kalajahi… - European Polymer …, 2020 - Elsevier
dendrimers in drug delivery including solubility improvement of hydrophobic drugs, Janus
dendrimers are used to improve solubility … different generations of Janus dendrimers. Since the …

[HTML][HTML] Properties and bioapplications of amphiphilic janus dendrimers: A Review

A Căta, IMC Ienașcu, MN Ştefănuț, D Roșu, OR Pop - Pharmaceutics, 2023 - mdpi.com
… water-soluble drug molecules. Amphiphilic Janus dendrimers can be adsorbed onto drug
offering a versatile platform for general use as stabilizing agents for drug suspensions [106]. …

Janus-type dendrimers: Synthesis, properties, and applications

F Najafi, M Salami-Kalajahi… - Journal of Molecular …, 2022 - Elsevier
Janus dendrimers have enhanced solubility, electrochemical … To improve the solubility of
hydrophobic drugs in water, … Two of the amphiphilic Janus dendrimers included galactose …

[HTML][HTML] Target-Specific Delivery and Bioavailability of Pharmaceuticals via Janus and Dendrimer Particles

J Jeevanandam, KX Tan, J Rodrigues, MK Danquah - Pharmaceutics, 2023 - mdpi.com
Janus particles and dendrimers have demonstrated their potential to improve the solubility
and stability of poorly water-soluble drugs… as silica-based amphiphilic Janus particles with …

[HTML][HTML] Janus dendrimers to assess the anti-HCV activity of molecules in cell-assays

M San Anselmo, A Lancelot, JE Egido… - Pharmaceutics, 2020 - mdpi.com
solubility of the bioactive compounds within the dendrimers and the improved antiviral activity
of some of the dendrimer/drug … here four novel amphiphilic Janus dendrimers thoughtfully …

Janus Dendrimers as Nanocarriers of Ibuprofen, Chlorambucil and their Anticancer Activity

LD Pedro-Hernández… - Pharmaceutical …, 2024 - ingentaconnect.com
amphiphilic copolymers, their dendritic counterparts, Janusdrug) on the other side, but its
biological activity was not determined [29]… Herein, we report the synthesis of Janus dendrimers

Amphiphilic Dendrimers for Drug Delivery

CA Omolo, RS Kalhapure, DR Sikwal… - Handbook of Materials …, 2020 - taylorfrancis.com
amphiphilic dendrimers and their utilization in drug delivery for the three classes of dendrimers
… The results of the encapsulation study indicated a 10-fold solubility enhancement for …

Structural and Surface Properties of Polyamidoamine (PAMAM)–Fatty Acid‐based Nanoaggregates Derived from Self‐assembling Janus Dendrimers

ML Yaddehige, I Chandrasiri, A Barker… - …, 2020 - Wiley Online Library
… In recent years, amphiphilic Janus dendrimers (JDs) have become a primary topic of … fields
of drug conjugation, drug and gene delivery, solubility enhancement of hydrophobic drugs, …

Nanomedical applications of amphiphilic dendrimeric micelles

GL Rodríguez-Acosta… - Current Medicinal …, 2021 - ingentaconnect.com
… related to the solubility and stability of antiviral drugs in water [93]… approach to synthesize
amphiphilic Janus dendrimers that self-… carrier, in areas such as drug delivery and catalysis. …

Janus-Type Dendrimers Based on Highly Branched Fluorinated Chains with Tunable Self-Assembly and 19F Nuclear Magnetic Resonance Properties

M Rosati, A Acocella, A Pizzi, G Turtù, G Neri… - …, 2022 - ACS Publications
… Formation of the sought amphiphilic dendrimers is evident from the presence in 1 H NMR
spectra of the peak at about 8 ppm related to the proton of the triazole ring (Figure S4). …