[HTML][HTML] AMPK, mitochondrial function, and cardiovascular disease

S Wu, MH Zou - International journal of molecular sciences, 2020 - mdpi.com
… of AMPK structure and regulation, and then focus on the recent advances toward understanding
how mitochondrial dysfunction controls AMPK and how AMPK, … , maintains mitochondrial

New insights into activation and function of the AMPK

GR Steinberg, DG Hardie - Nature reviews Molecular cell biology, 2023 - nature.com
… on the regulation of … for AMPK involved in autophagy, ferroptosis, mitochondrial and
lysosomal homeostasis and DNA repair. Finally, we discuss recent findings on the role of AMPK in …

AMPK, metabolism, and vascular function

C Rodríguez, M Muñoz, C Contreras… - The FEBS …, 2021 - Wiley Online Library
… In this review, we summarize and discuss the role of AMPK in the regulation of blood flow in
… ) mitochondrial uptake by CPT1. Consequently, AMPK activation favors FFA mitochondrial

[HTML][HTML] AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner

AP Seabright, NHF Fine, JP Barlow, SO Lord… - The FASEB …, 2020 - ncbi.nlm.nih.gov
… and is regulated by AMPK‐dependent signaling. Thus, … that AMPK activation stimulates
mitochondrial fission via … , we found that AMPK activation stimulates TBK1 activation in a PINK1‐…

[HTML][HTML] Spatial regulation of AMPK signaling revealed by a sensitive kinase activity reporter

DL Schmitt, SD Curtis, AC Lyons, J Zhang… - Nature …, 2022 - nature.com
… in regulating cytoplasmic, lysosomal, and mitochondrial AMPK activity. Finally, we measure
AMPK activity with ExRai AMPKAR and identify a regulatory mechanism for nuclear AMPK

[HTML][HTML] Emerging role of cAMP/AMPK signaling

M Aslam, Y Ladilov - Cells, 2022 - mdpi.com
… insight into the regulation of the cAMP/AMPK axis. In … adenylyl cyclase in regulating basal
and induced AMPK activity has … understanding of the regulation of the cAMP/AMPK axis and …

AMPK signaling and its targeting in cancer progression and treatment

CC Hsu, D Peng, Z Cai, HK Lin - Seminars in cancer biology, 2022 - Elsevier
… In this review, we will describe the upstream regulation and downstream substrates of
AMPK under physiological stresses. Moreover, we will elaborate the biological functions of …

Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy

JC Drake, RJ Wilson, RC Laker… - Proceedings of the …, 2021 - National Acad Sciences
… However, these experimental findings do not exclude the possibility that mitoAMPK may
regulate mitochondrial dynamics, such as mitochondrial fission, under physiological conditions. …

[HTML][HTML] Mitophagy: molecular mechanisms, new concepts on parkin activation and the emerging role of AMPK/ULK1 axis

R Iorio, G Celenza, S Petricca - Cells, 2021 - mdpi.com
… the molecular mechanisms that regulate mitochondrial removal and … AMPK and mitochondrial
biology, we also highlight recent advances in the role of the AMPK/ULK1 axis in regulating

Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1

N Malik, BI Ferreira, PE Hollstein, SD Curtis, E Trefts… - Science, 2023 - science.org
… whether AMPK may regulateAMPK may regulate FNIP1 to control TFEB independently of
AAs. Analysis of the FNIP1 protein sequence revealed four sites that match the optimal AMPK