High-speed atomic force microscopy reveals the structural dynamics of the amyloid-β and amylin aggregation pathways
T Watanabe-Nakayama, BR Sahoo… - International journal of …, 2020 - mdpi.com
… Here, we review and discuss the HS-AFM imaging of amyloid aggregation and strategies
to optimize the experiments showing findings from Aβ and amylin, which is associated with …
to optimize the experiments showing findings from Aβ and amylin, which is associated with …
Cryo‐electron Microscopy Imaging of Alzheimer's Amyloid‐beta 42 Oligomer Displayed on a Functionally and Structurally Relevant Scaffold
… Amyloid-β peptide (Aβ) oligomers are pathogenic species of amyloid aggregates in …
The Aβ42-αHL oligomers will allow many of the features of the wild-type amyloid oligomers …
The Aβ42-αHL oligomers will allow many of the features of the wild-type amyloid oligomers …
Super‐resolution infrared imaging of polymorphic amyloid aggregates directly in neurons
O Klementieva, C Sandt, I Martinsson… - Advanced …, 2020 - Wiley Online Library
… polymorphism of amyloid aggregates which may exist already at the subcellular level. …
Thus, we demonstrate the potential of O-PTIR microscopy to image molecular structures at the …
Thus, we demonstrate the potential of O-PTIR microscopy to image molecular structures at the …
Three-dimensional real time imaging of amyloid β aggregation on living cells
M Kuragano, R Yamashita, Y Chikai, R Kitamura… - Scientific reports, 2020 - nature.com
… 42 aggregation with living cells by applying the QD imaging … fluorescence microscopy
confirmed Aβ 42 aggregation imaging … aggregates using a conventional fluorescence microscope (…
confirmed Aβ 42 aggregation imaging … aggregates using a conventional fluorescence microscope (…
Near-infrared fluorescence lifetime imaging of amyloid-β aggregates and tau fibrils through the intact skull of mice
… amyloid-β deposits and to neurofibrillary tangles, and allows for the microscopic imaging of
amyloid-β and tau aggregates … shift when bound to amyloid-β and tau aggregates than when …
amyloid-β and tau aggregates … shift when bound to amyloid-β and tau aggregates than when …
Characterization of substrates and surface-enhancement in atomic force microscopy infrared analysis of amyloid aggregates
… Considering the commercial costs of the substrates analyzed in our study, we found that
Si, CaF 2 , and ZnS are the best candidates for AFM-IR imaging of amyloid aggregates, see …
Si, CaF 2 , and ZnS are the best candidates for AFM-IR imaging of amyloid aggregates, see …
In Vivo Brain Imaging of Amyloid-β Aggregates in Alzheimer's Disease with a Near-Infrared Fluorescent Probe
J Wu, C Shao, X Ye, X Di, D Li, H Zhao, B Zhang… - ACS …, 2021 - ACS Publications
… (23) Herein, we report a new NIR fluorescent probe for imaging Aβ aggregates from in vitro
… , which was confirmed by TEM (transmission electron microscopy) imaging. It was observed …
… , which was confirmed by TEM (transmission electron microscopy) imaging. It was observed …
Different aggregation pathways and structures for Aβ40 and Aβ42 peptides
… aggregation pathways of Aβ isoforms lead to the amyloid … atomic force microscopy (AFM),
which is able to image the small-… can be converted to fibrils, we consider AFM images of the …
which is able to image the small-… can be converted to fibrils, we consider AFM images of the …
Biophysical processes underlying cross-seeding in amyloid aggregation and implications in amyloid pathology
MI Ivanova, Y Lin, YH Lee, J Zheng… - Biophysical chemistry, 2021 - Elsevier
… amyloid proteins. Indeed, only some pairs of amyloid proteins promote amyloid aggregation
… Transmission electron microscope (TEM) images of SEVI fibrils formed in the absence of …
… Transmission electron microscope (TEM) images of SEVI fibrils formed in the absence of …
[HTML][HTML] A FRET pair for quantitative and superresolution imaging of amyloid fibril formation
Á Ruiz-Arias, R Jurado, F Fueyo-González… - Sensors and Actuators B …, 2022 - Elsevier
… fluorescence lifetime imaging microscopy (FLIM). … for detecting different types of amyloid
aggregates. However, the … AQui for pre-amyloid aggregate characterization and classification …
aggregates. However, the … AQui for pre-amyloid aggregate characterization and classification …
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