… To inform decision-makers whether the common practice of dosing outside of guidelines
produces optimal patient outcomes, it is necessary to systematically evaluate the clinical and …

… the optimal dose and regimen, the PK profiles and AUCs of several once-or-twice-daily dosing
regimens (with a total daily dose … doses for AF are given once daily, but twice-daily dosing …

… recommend dosing DOAC according to the label. Prescribing inappropriate low DOAC doses
… Moreover, strict DOAC adherence is paramount, as missing a DOAC dose can quickly lead …

… Therefore, optimal dosing in severe CKD is unclear owing to the lack of trial … optimal
apixaban dosing is thus of great clinical importance in this high-risk population. Apixaban dosing …

… Therefore, when the rivaroxaban dose was delayed or missed, optimal remedial dosing
could help patients to restore the rivaroxaban concentration, FXa activity, or PT to the on-therapy …

… monotherapy to inappropriately low doses of NOACs. However, inappropriate NOAC
dosing in the older AF patients still deprives them of optimal thromboprotection. Intensive …

… Such practice is common in Asia, and we aimed to evaluate the use of low-dose NOACs
and their impact on clinical outcomes among Chinese patients with atrial fibrillation. …

… optimal NOAC dosage as well as the preferred TAT and DAT duration following PCI in each
individual patient, as recommended by the latest ESC guidelines for AF [1, 50]. Nevertheless…

… Atrial fibrillation causes one-fifth of ischemic strokes, with a … for stroke prevention in atrial
fibrillation, initiation after stroke is … The dose may be reduced if recommended by the relevant …

… of thromboembolism in non-valvular atrial fibrillation (NVAF) [1]… Selecting the preferable
DOAC in an appropriate dose can … ) have different doses and specific dose reduction criteria that …