Injury of muscular but not cutaneous nerve drives acute neuropathic pain in rats

J Zhu, Z Chen, Y Fang, W Duan, Y Xie, C Ma - Neuroscience Bulletin, 2020 - Springer
… to transect peripheral nerves in awake rats to investigate the role of muscular nerves in
acute neuropathic pain. The tibial (both muscular and cutaneous), gastrocnemius–soleus (GS) (…

The neurophysiological impact of experimentally-induced pain on direct muscle spindle afferent response: a scoping review

CR Lima, PK Sahu, DF Martins… - Frontiers in Cellular …, 2021 - frontiersin.org
… tibialis anterior muscle or subdermal tissues. In pre-clinical studies, muscle pain was induced
… Conclusion: Clinical studies in awake humans reported that experimentally-induced pain

AKCa3.1 Channel Opener, ASP0819, Modulates Nociceptive Signal Processing from Peripheral Nerves in Fibromyalgia-Like Pain in Rats

N Takeshita, T Oe, T Kiso, S Kakimoto - Journal of Pain Research, 2021 - Taylor & Francis
… distension test was performed in awake and unrestrained rats. A 5-… muscle pain that persists
for 1 week or longer in rats. Citation16 The decreased levels of biogenic amines in RIM rats

Muscle injury induces an increase in total and non-rapid eye movement sleep time

T Vanneau, M Quiquempoix, MC Erkel, C Drogou… - Sleep, 2023 - academic.oup.com
… wakefulness and intensifies as one remains awake [17]. Sleep is … of skeletal muscle injury
on sleep characteristics in rats. … signs of excessive pain, it is certain that the muscle injury is …

Back mechanical sensitivity assessment in the rat for mechanistic investigation of chronic back pain

H Khosravi, N Eskandari, B Provencher… - JoVE (Journal of …, 2022 - jove.com
… Apply the filament only when the animal is awake, standing on its four paws, and not moving.
… back muscles from CFA rats and controls 30 . (A) Healthy back muscle from a control rat 14 …

Effects of administration of α2 adrenergic receptor agonist into psoas major muscle on inflammatory pain induced by injection of complete Freund's adjuvant in rats

X Guo, Y Xue, W Ji, J Liang, Z Qingshi - Molecular Pain, 2022 - journals.sagepub.com
… placed back into the cage after they were completely awake. … muscle exerted analgesic
effect on lower limb pain in rats, … did not relieve cold ectopic pain induced by acetone and did …

Mechanism of dexmedetomidine preconditioning on spinal cord analgesia in rats with functional chronic visceral pain

J Li, H Tang, W Tu - Acta Cirúrgica Brasileira, 2022 - SciELO Brasil
… After the rats were awake, the stimulation intensity of colorectal dilatation included 80, 60, 40,
and … When AWR score was 2 points, the abdominal muscles began to contract. When AWR …

Regional cerebral metabolic levels and turnover in awake rats after acute or chronic spinal cord injury

L Wu, Z Niu, X Hu, H Liu, S Li, L Chen… - The FASEB …, 2020 - repository.uwl.ac.uk
… Here, adult Sprague-Dawley rats were divided into acute and chronic treatment groups and
sham groups with day-matched periods. The Basso, Beatte, and Bresnahan scores method …

[HTML][HTML] … pulsed ultrasound phonophoresis with diclofenac alleviated inflammation and pain via downregulation of M1 macrophages in rats with carrageenan-induced …

R Sasaki, J Sakamoto, Y Honda, S Motokawa… - Neurobiology of Pain, 2024 - Elsevier
awakening. Then, the rats were anesthetized and their knee joint swelling was measured.
Finally, we administered the drug and/or LIPUS. Before measuring PPT and PWT, the rats

Chronic pain impact on rodents' behavioral repertoire

AM Cunha, J Pereira-Mendes, A Almeida… - Neuroscience & …, 2020 - Elsevier
… chronic pain (CP) pathophysiology and to test for potential treatments. Pain assessment in
CP … of CP-related problems which include ongoing pain, depression, anxiety, disrupted sleep …