Epigenome-wide DNA methylation signature of benzo [a] pyrene exposure and their mediation roles in benzo [a] pyrene-associated lung cancer development

H Meng, G Li, W Wei, Y Bai, Y Feng, M Fu… - Journal of hazardous …, 2021 - Elsevier
… Our results highlight DNA methylation alterations as potential … -wide DNA methylation
changes associated with B[a]P exposure is still unknown and the extent to which DNA methylation

[HTML][HTML] Dynamic changes of DNA methylation induced by benzo (a) pyrene in cancer

H Wang, B Liu, H Chen, P Xu, H Xue, J Yuan - Genes and Environment, 2023 - Springer
hypermethylation, resulting in cancer initiation and progression. Here we summarized …
changes in DNA methylation in BaP exposure, and revealed the methylation of DNA plays a …

[HTML][HTML] Influence of benzo (a) pyrene on different epigenetic processes

B Bukowska, P Sicińska - International Journal of Molecular Sciences, 2021 - mdpi.com
… The results showed the tissue specificity of global DNA methylation, ie, the total genomic
DNA methylation level was significantly decreased in the blood and liver but not in the pancreas…

The effect of benzo [alpha] pyrene on DNA methylation and telomerase activity in human normal and cancer cells

R Zarei, D Moghadam, MM Sarabi, F Naghibalhossaini - Toxicology in Vitro, 2022 - Elsevier
DNA methylation in human normal and cancer cells. … DNA methylation changes are two
hallmarks of cancer cells. Previous studies have demonstrated that the global DNA methylation

The role of DNA methylation on gene expression in the vertebrae of ancestrally benzo [a] pyrene exposed F1 and F3 male medaka

T Wan, J Mo, DWT Au, X Qin, NYK Tam, RYC Kong… - Epigenetics, 2023 - Taylor & Francis
… global methylation levels and decreased global DNA methylation … Reduced global DNA
methylation coupled with the … embryos, which suggests that DNA methylation may play a role in …

Study of DNA methylation of hsd17β, er and reproductive endocrine disrupting effects in female Chlamys farreri under benzo [a] pyrene stress

J Tang, A Song, L Pan, J Miao, Z Li, Y Zhou - Environmental Pollution, 2023 - Elsevier
… levels of DNA methylation levels. In summary, current research on DNA methylation of marine
… the changes in global methylation, lacking research on DNA methylation process and the …

Benzo [a] pyrene-induced multigenerational changes in gene expression, behavior, and DNA methylation are primarily influenced by paternal exposure

Z Pandelides, MC Sturgis, C Thornton, N Aluru… - Toxicology and Applied …, 2023 - Elsevier
… To assess molecular changes associated with BaP exposure, we conducted transcriptome
and DNA methylation profiling in F0 gametes (sperm and eggs) and F1 embryos (10 hpf) from …

[HTML][HTML] DNA methylation changes from primary cultures through senescence-bypass in Syrian hamster fetal cells initially exposed to benzo [a] pyrene

D Desaulniers, C Cummings-Lorbetskie, K Leingartner… - Toxicology, 2023 - Elsevier
… of carcinogen-induced DNA methylation changes from primary … , to cells exposed for 7
days to benzo[a]pyrene, and to cells at the … DNA methylation changes identified by reduced …

[HTML][HTML] Acute benzo[a]pyrene exposure induced oxidative stress, neurotoxicity and epigenetic change in blood clam Tegillarca granosa

B Guo, D Feng, Z Xu, P Qi, X Yan - Scientific Reports, 2021 - nature.com
… The correlation analysis showed that the global DNA methylation was negatively correlated
… stress and neurotoxicity, and the global DNA methylation was inhibited to increase the …

Benzo [a] pyrene osteotoxicity and the regulatory roles of genetic and epigenetic factors: A review

J Mo, DWT Au, J Guo, C Winkler… - Critical Reviews in …, 2022 - Taylor & Francis
… pollutant, benzo[a]pyrene (BaP… DNA methylation and/or histone modifications, affecting
target gene expression/activity; (ii) dysregulation of bone genes through altered DNA methylation