A novel gene prognostic signature based on differential DNA methylation in breast cancer

C Zhu, S Zhang, D Liu, Q Wang, N Yang… - Frontiers in …, 2021 - frontiersin.org
… revealed the DNA methylation landscape and established promising methylation and
methylation-… This study will help unveil the significance of DNA methylation in BC and might help …

A seven‐DNA methylation signature as a novel prognostic biomarker in breast cancer

C Tao, R Luo, J Song, W Zhang… - Journal of Cellular …, 2020 - Wiley Online Library
… on this signature, we divided the samples according to age, subtype, and cancer staging,
and … A seven-DNA methylation signature was identified in this study. It has a good diagnostic …

DNA methylation biomarkers for noninvasive detection of triple‐negative breast cancer using liquid biopsy

M Manoochehri, N Borhani… - … Journal of Cancer, 2023 - Wiley Online Library
DNA methylation data derived from TNBC and normal breast … samples of sorted blood and
mammary cells. Differentially … of cfDNA-based methylation signatures as noninvasive liquid …

Integrative analysis of DNA methylation and gene expression to determine specific diagnostic biomarkers and prognostic biomarkers of breast cancer

M Zhang, Y Wang, Y Wang, L Jiang, X Li… - Frontiers in Cell and …, 2020 - frontiersin.org
… Although previous studies have reported a cluster of aberrant promoter methylation … of these
DNA methylation changes. Here we aimed to identify specific DNA methylation signatures in …

Integrative analysis of DNA methylation and gene expression profiles identified potential breast cancer-specific diagnostic markers

X Liu, Y Peng, J Wang - Bioscience reports, 2020 - portlandpress.com
… a robust DNA methylation-based breast cancer-specific diagnostic signature. Genome-wide …
In the present study, we systematically compared overall DNA methylation profiles of BRCA …

A DNA methylation-based panel for the prognosis and diagnosis of patients with breast cancer and its mechanisms

XP Liu, J Hou, C Chen, L Guan, HK Hu… - Frontiers in molecular …, 2020 - frontiersin.org
… on DNA methylation sites. In the present study, we tried to develop a multi-5′-C-phosphate-G-3′
(CpG) site based DNA methylation … ) versus the 7-CpG methylation signature in the …

Deciphering the methylation landscape in breast cancer: diagnostic and prognostic biosignatures through automated machine learning

M Panagopoulou, M Karaglani, VG Manolopoulos… - Cancers, 2021 - mdpi.com
DNA methylation plays an important role in breast cancer (BrCa) pathogenesis and could …
Similarly, in our cohort, methylation-based signatures could not predict survival in primary …

DNA methylation markers panel can improve prediction of response to neoadjuvant chemotherapy in luminal B breast cancer

VO Sigin, AI Kalinkin, EB Kuznetsova, OA Simonova… - Scientific Reports, 2020 - nature.com
… that it is not the regimen but mostly the tumor biological status that predetermines its sensitivity
to cytostatic NACT, and this status may be reflected by specific epigenetic signatures that …

DNA methylation and breast cancer: A way forward

MT Vietri, G D'elia, G Benincasa… - International …, 2021 - spandidos-publications.com
… The aim of the present review was to update the pathogenic DNA methylation signatures
The potential role of these signatures as novel prognostic and diagnostic biomarkers, as …

Circulating cell-free DNA-based methylation patterns for breast cancer diagnosis

X Zhang, D Zhao, Y Yin, T Yang, Z You, D Li… - … Breast Cancer, 2021 - nature.com
… on computational analysis of the DNA methylation profiles from The Cancer Genome Atlas
(… profiling, we developed a highly sensitive, targeted DNA methylation sequencing technique …