Breast milk: A source of functional compounds with potential application in nutrition and therapy
C Sánchez, L Franco, P Regal, A Lamas, A Cepeda… - Nutrients, 2021 - mdpi.com
… For this reason, its therapeutic potential has begun to be tested … , milk exosomes have
notable advantages over other drug … But also, exosomes from bovine milk are used as drug …
notable advantages over other drug … But also, exosomes from bovine milk are used as drug …
Infant drug exposure via breast milk
RHJ Verstegen, PO Anderson… - British Journal of Clinical …, 2022 - Wiley Online Library
… concentrations in infant serum do not reach a level known to be therapeutic in adults unless
drug clearance is markedly lower than the adult level on a weight basis. RID is a function of …
drug clearance is markedly lower than the adult level on a weight basis. RID is a function of …
More than nutrition: Therapeutic potential of breast milk-derived exosomes in cancer
KU Kim, WH Kim, CH Jeong, DY Yi, H Min - International Journal of …, 2020 - mdpi.com
… -derived exosomes exert various physiological and therapeutic … In addition, the milk-derived
exosomes are developed as drug … of HBM and their therapeutic potential, in particular of …
exosomes are developed as drug … of HBM and their therapeutic potential, in particular of …
The therapeutic potential of breast milk-derived extracellular vesicles
JD Galley, GE Besner - Nutrients, 2020 - mdpi.com
… may mediate its therapeutic effects. This review offers an update on the therapeutic potential
of exosomes/EVs in disease, with a focus on EVs present in human breast milk and their …
of exosomes/EVs in disease, with a focus on EVs present in human breast milk and their …
[HTML][HTML] A comprehensive review on non-clinical methods to study transfer of medication into breast milk–A contribution from the ConcePTION project
N Nauwelaerts, N Deferm, A Smits, C Bernardini… - Biomedicine & …, 2021 - Elsevier
… breastfeeding is lacking for most medications. This leads to discontinuation of either breastfeeding
… maternal medication into the human breast milk, and subsequent neonatal systemic …
… maternal medication into the human breast milk, and subsequent neonatal systemic …
Prediction of drug concentrations in milk during breastfeeding, integrating predictive algorithms within a physiologically‐based pharmacokinetic model
K Abduljalil, A Pansari, J Ning… - CPT: pharmacometrics & …, 2021 - Wiley Online Library
… Quantification of drugs in breast milk is important to raise our awareness of the potential …
outside the model assumptions for drugs with narrow therapeutic index. Because the described …
outside the model assumptions for drugs with narrow therapeutic index. Because the described …
Development of a generic physiologically‐based pharmacokinetic model for lactation and prediction of maternal and infant exposure to ondansetron via breast milk
KM Job, A Dallmann, S Parry, G Saade… - … & Therapeutics, 2022 - Wiley Online Library
… Because obtaining PK data is challenging during the early postpartum period and modeling
of drug passage into human breast milk has been limited, 22 we report the development of a …
of drug passage into human breast milk has been limited, 22 we report the development of a …
Excretion of antipsychotics into the amniotic fluid, umbilical cord blood, and breast milk: a systematic critical review and combined analysis
G Schoretsanitis, AA Westin… - Therapeutic drug …, 2020 - journals.lww.com
… into the breast milk based on ionization; however, breast milk concentrations were still …
plasma to be excreted into the breast milk, as only the unbound drug concentration can cross cell …
plasma to be excreted into the breast milk, as only the unbound drug concentration can cross cell …
Human breast milk: from food to active immune response with disease protection in infants and mothers
GAG Lokossou, L Kouakanou, A Schumacher… - Frontiers in …, 2022 - frontiersin.org
… Breast milk components such as, non-immune and immune … breast milk with regard to
disease protection. We will shed some light on the mechanisms underlying the roles of breast milk …
disease protection. We will shed some light on the mechanisms underlying the roles of breast milk …
[HTML][HTML] Concentrations of antiseizure medications in breast milk of lactating women with epilepsy: A systematic review with qualitative synthesis
R Shawahna, L Zaid - Seizure, 2022 - Elsevier
… concentration of the ASM in breastmilk multiplied by the amount of breastmilk intake (150
mL… infant dose received via breastmilk was equal to the maternal therapeutic dose per weight. …
mL… infant dose received via breastmilk was equal to the maternal therapeutic dose per weight. …
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