Role of c-Jun N-terminal kinase (JNK) in obesity and type 2 diabetes

JHM Yung, A Giacca - Cells, 2020 - mdpi.com
signals can be integrated into cellular responses, which can provide multiple points of regulation,
as well as points of crosstalk with other signaling pathways … factors such as c-Jun, ATF2…

The multifaceted output of c-Jun biological activity: focus at the junction of CD8 T cell activation and exhaustion

AG Papavassiliou, AM Musti - Cells, 2020 - mdpi.com
c-Jun/AP-1 transcription factor in different types of mammal cells, this review focus on the
current understanding of c-Jun/… C-Jun and/or AP-1 mediate signaling pathways that ultimately …

[HTML][HTML] … kinase inhibitor, JNK-IN-8 suppresses mesenchymal profile of PTX-resistant MCF-7 cells through modulating PI3K/Akt, MAPK and Wnt signaling pathways

PO Kilbas, O Sonmez, P Uysal-Onganer, AC Gurkan… - Biology, 2020 - ncbi.nlm.nih.gov
… According to our results that the stress-activated MAPK signaling members were … of a
specific c-Jun N-terminal kinase JNK inhibitor on MAPK, EMT, Wnt signaling members associated …

The lincRNA JUNI regulates the stress-dependent induction of c-Jun, cellular migration and survival through the modulation of the DUSP14-JNK axis

V Kumar, X Sabaté-Cadenas, I Soni, E Stern, C Vias… - Oncogene, 2024 - nature.com
… hanging insert membrane and the crossing cells were stained with methylene blue and
photographed 16 later. C Graphic presentation of cells crossing the Millicell membrane16 hours …

c-Jun as a one-way valve at the naive to primed interface

D Li, L Luo, L Guo, C Wu, R Zhang, Y Peng, M Wu… - Cell & Bioscience, 2023 - Springer
… that c-Jun acts as a one-way valve to preserve the primed state and impair reversion to the
naïve state. c-Jun is … The results of this study indicate that c-Jun can function as a chromatin …

Recent advances in c-Jun N-terminal kinase (JNK) inhibitors

G Li, W Qi, X Li, J Zhao, M Luo… - Current Medicinal …, 2021 - ingentaconnect.com
… Stress-activated MAPK signaling pathways (upon activation by extracellular stress, a
variety of receptor-associated signaling mechanisms lead to the activation of mitogen-activated …

Activation of c-Jun by human cytomegalovirus UL42 through JNK activation

T Koshizuka, N Inoue - PLoS One, 2020 - journals.plos.org
… HCMV UL42 induced AP-1 signaling by the activation of the c-Jun/JNK pathway. UL42 …
c-Jun Ser63, one of two JNK-mediated phosphorylation sites required for the promotion of c-Jun

[HTML][HTML] c-Jun phosphorylated by JNK is required for protecting Gli2 from proteasomal-ubiquitin degradation by PGE2-JNK signaling axis

J Yang, J Wang, Y Zhang, W Huang, S Zhang… - … et Biophysica Acta (BBA …, 2023 - Elsevier
… that c-Jun interacts with multiple signaling pathways to amplify or integrate the effects of
different signaling pathways in … In addition, despite few human cancers having causative c-Jun

[HTML][HTML] Isoform-specific functions of c-Jun N-terminal kinase 1 and 2 in lung ischemia-reperfusion injury through the c-Jun/activator protein-1 pathway

J Tan, W Gao, W Yang, X Zeng, L Wang… - The Journal of Thoracic …, 2021 - Elsevier
… cellular responses through regulation of the JNK/c-Jun/AP-1 pathway, we … c-Jun, was
carried out by Western blotting and detected by a specific antibody against phosphorylated c-Jun

Crosstalk between NLRP12 and JNK during hepatocellular carcinoma

S Khan, H Zaki - International journal of molecular sciences, 2020 - mdpi.com
… by several inflammatory signaling pathways, including … of the c-Jun N-terminal kinase (JNK)
signaling pathway. Here, … the portal vein after crossing the intestinal epithelial barrier. …