The Fraser complex interconnects tissue layers to support basal epidermis and osteoblast integrated morphogenesis underlying fin skeletal patterning

AE Robbins, SG Horst, VM Lewis, S Stewart… - bioRxiv, 2023 - biorxiv.org
… Individual rays comprise two calcified and osteoblast-lined hemirays encasing intra-ray 70 …
mutants by Alcian Blue and Alizarin Red staining of cartilage and calcified bone, respectively, …

Chondrogenesis defines future skeletal patterns via cell transdifferentiation from chondrocytes to bone cells

Y Jing, Z Wang, H Li, C Ma, J Feng - Current osteoporosis reports, 2020 - Springer
… secrete unique matrix proteins and calcify cartilage matrices. … of dead chondrocytes and
calcified cartilage) and osteoblast … the formation of the vertebrate endoskeleton, as the cartilage …

Zebrafish: a resourceful vertebrate model to investigate skeletal disorders

F Tonelli, JW Bek, R Besio, A De Clercq… - Frontiers in …, 2020 - frontiersin.org
… with different cellularity and matrix composition exist in wild … of a dermal skeleton and an
endoskeleton. Scales, polarized … to start, matrix surrounding the chondrocytes must calcify so …

ROCK and the actomyosin network control biomineral growth and morphology during sea urchin skeletogenesis

E Hijaze, T Gildor, R Seidel, M Layous, M Winter… - Elife, 2024 - elifesciences.org
… This valuable study addresses the role of Rho-associated coiled-coil kinase (ROCK) and
the cytoskeleton in the initiation and growth of the calcified endoskeleton of sea urchin embryos…

More bone with less minerals? The effects of dietary phosphorus on the post-cranial skeleton in zebrafish

S Cotti, A Huysseune, W Koppe, M Rücklin… - International journal of …, 2020 - mdpi.com
… trigger soft tissue calcification and bone hypermineralisation. … increased soft tissue calcification,
particularly in the kidney [… Focusing on both endoskeletal and dermal skeletal elements, …

Skeletal endocrinology: Where evolutionary advantage meets disease

N Jaschke, W Sipos, LC Hofbauer, TD Rachner… - Bone Research, 2021 - nature.com
endoskeleton imposed the risk of transient and/or permanent accumulation of phosphate
within the body, which is highly toxic and evokes diseases such as vascular calcification. …

Exercise improves subchondral bone microenvironment through regulating bone-cartilage crosstalk

S Zhang, T Li, Y Feng, K Zhang, J Zou… - Frontiers in …, 2023 - frontiersin.org
matrix, eroding the cartilage matrix while secreting type I collagen to form cancellous bone.
Osteoblasts in the periosteum then secrete a highly calcified matrix that … bone endoskeletal

Carbonic anhydrases in development: morphological observations and gene expression profiling in sea urchin embryos exposed to acetazolamide

F Zito, R Bonaventura, C Costa, R Russo - Open Biology, 2023 - royalsocietypublishing.org
… A specific role in embryonic calcification had been shown in P. lividus and H. tuberculata, as
well … endoskeleton is composed of calcium carbonate mineral and a soluble organic matrix, …

Divergent Expression of SPARC, SPARC-L, and SCPP Genes During Jawed Vertebrate Cartilage Mineralization

A Romero, N Leurs, D Muñoz… - Frontiers in …, 2021 - frontiersin.org
… of SPARC, SPARC-L and the SCPP members during cartilage mineralization remains
limited, and, in this study, we examined the expression of these genes during endoskeletal

Big insight from the little skate: Leucoraja erinacea as a developmental model system

JA Gillis, S Bennett, KE Criswell, J Rees… - Current Topics in …, 2022 - Elsevier
calcified surface of some endoskeletal elements) stained red. The vast majority of the skate
endoskeleton … sheath that enwraps the cartilaginous endoskeleton). These progenitor cells co…