… of resistance to currently available targeted therapies have posed the obstacle in the …
pathogenesis more comprehensively, which might lead to more substantial progress in therapeutic …

… PDAC have revealed new opportunities for early detection and targeted therapy of PDAC.
In this review, we discuss the pathogenesis of PDAC, including molecular alterations in tumor …

… Understanding the complexity of CSCs may facilitate the development of targeted therapeutic
drugs against cancer. Taken together, the major targets mentioned in this review highlight …

Due to the advantages in efficacy and safety compared with traditional chemotherapy drugs,
targeted therapeutic drugs have become mainstream cancer treatments. Since the first …

… For instance, in a study of ~10,000 solid tumors, patients with gastrointestinal stromal
tumors, thyroid cancer, breast cancer, melanoma or glioma received specific targeted therapies …

… Overall, this highlights the need for potent ECM-targeting therapies. … In addition to the
aforementioned targeted therapeutic strategies, combination therapies have gained popularity as …

… and progression of colon cancer. Therefore, the Wnt signaling pathway plays an important
role in the pathogenesis of diseases, especially the pathogenesis of colorectal cancer (CRC). …

… repair in the promotion of cancer and cancer therapy developed, then we summarize the …
with targeted cancer therapy, highlighting the specific proteins behind targeting DNA damage …

… targeted therapy, immunotherapy, and nanoparticle-based delivery systems. In the current
review, we primarily focus on the targeted therapy … Global clinical trials of targeted therapy in …

… targeted therapy and regulation of cancer cell death. Apoptosis has been recognized as a
critical intracellular process that maintains organism homeostasis and controls cell population. …