Right versus left ventricular remodeling in heart failure due to chronic volume overload

T Havlenova, P Skaroupkova, M Miklovic… - Scientific Reports, 2021 - nature.com
Limited utility of regional RV function indexes is also … myocardial remodeling (Table 3), in
contrast to volumetric parameters. … NRAP overexpression in the mouse leads to right ventricular

Cardiac fibrosis in the pressure overloaded left and right ventricle as a therapeutic target

K Schimmel, K Ichimura, S Reddy, F Haddad… - … in Cardiovascular …, 2022 - frontiersin.org
… right and left ventricular reactive fibrosis on cardiac function, … However, inducible
overexpression of an inactive TGF-β type … amounted to data that are limited or conflicting. We here …

[HTML][HTML] Spatiotemporal transcriptome analysis reveals critical roles for mechano-sensing genes at the border zone in remodeling after myocardial infarction

S Yamada, T Ko, S Hatsuse, S Nomura… - Nature Cardiovascular …, 2022 - nature.com
… and play a critical role in left ventricular remodeling after MI. An … BZ of the pMI day 1 heart,
we overexpressed Csrp3 and short … the sections from limited areas of the human heart 14 , our …

Tisp40 prevents cardiac ischemia/reperfusion injury through the hexosamine biosynthetic pathway in male mice

X Zhang, C Hu, ZG Ma, M Hu, XP Yuan… - Nature …, 2023 - nature.com
… -restricted Tisp40 overexpression ameliorates I/R-induced oxidative stress, apoptosis and
acute cardiac injury, and modulates cardiac remodeling … the left ventricles of ischemic heart

Mir-30d regulates cardiac remodeling by intracellular and paracrine signaling

J Li, AM Salvador, G Li, N Valkov, O Ziegler… - Circulation …, 2021 - Am Heart Assoc
… generally produce reverse left ventricular remodeling. In this … with genetic overexpression
of miR-30d (Figure 1B), cardiac … When restricted to pathways relevant to cardiac remodeling, …

Fibroblasts activation by embryonic signal switching: A novel mechanism of placental growth factor-induced cardiac remodeling

L Kitasato, M Yamaoka-Tojo, M Suzuki, S Nakahara… - Placenta, 2024 - Elsevier
cardiac remodeling, by stimulating with AngII and using mouse cardiac and PlGF overexpressed
… has very limited ability for regenerations [54]. It is well known that immediately after birth…

The Application Potential and Advance of Mesenchymal Stem Cell‐Derived Exosomes in Myocardial Infarction

X Wang, Y Tang, Z Liu, Y Yin, Q Li, G Liu… - Stem cells …, 2021 - Wiley Online Library
… cardiomyocytes and heart failure (HF) due to the restricted blood … to improve cardiac function
and reverse heart remodeling. … -overexpressing lentiviruses in a mouse model of myocardial

Post-myocardial infarction heart failure and long-term high-fat diet: Cardiac endoplasmic reticulum stress and unfolded protein response in Sprague Dawley rat model

K Momot, K Krauz, K Czarzasta, J Tomaszewski… - PLoS …, 2024 - journals.plos.org
… effects on the heart, whereas overexpression of nNOS and … studied markers in the left
ventricle was significant limitations. … , as it restricted our ability to evaluate cardiac function. Given …

[HTML][HTML] Nephronectin promotes cardiac repair post myocardial infarction via activating EGFR/JAK2/STAT3 pathway

Y Zhang, D Wang, Z Zhao, L Liu, G Xia… - … Journal of Medical …, 2022 - ncbi.nlm.nih.gov
… a system overexpressing NPNT locally in mouse heart by … cardiac function, limited infarct
size, alleviated cardiac fibrosis… -term left ventricular remodelling to prevent the transition to heart

Exosomes from SIRT1-overexpressing ADSCs restore cardiac function by improving angiogenic function of EPCs

H Huang, Z Xu, Y Qi, W Zhang, C Zhang… - … Therapy-Nucleic Acids, 2020 - cell.com
… the recovery of myocardial function with reduced infarct size and post-AMI left ventricular
remodeling, induced vasculogenesis, and decreased AMI-induced myocardial inflammation. …