Outcomes in patients with hypertrophic cardiomyopathy and left ventricular systolic dysfunction

EJ Rowin, BJ Maron, RT Carrick, PP Patel… - Journal of the American …, 2020 - jacc.org
… predictors of heart failure progression in HCM patients with systolic dysfunction. … patients
who experienced a stable clinical course versus those who progressed to refractory heart failure

Assessing left ventricular systolic function: from ejection fraction to strain analysis

BP Halliday, R Senior, DJ Pennell - European Heart Journal, 2021 - academic.oup.com
systolic function and cardiac output despite a normal EF. This is particularly pertinent amongst
patients with heart failure with preserved EF (HF-PEF) and hypertrophic cardiomyopathy (…

Hypertrophic cardiomyopathy with left ventricular systolic dysfunction: insights from the SHaRe registry

P Marstrand, L Han, SM Day, I Olivotto, EA Ashley… - Circulation, 2020 - Am Heart Assoc
systolic dysfunction or death-equivalent outcomes of cardiac transplantation or LVAD
implantation (30 patients … risk of developing impaired LV function after SRT 20 and emphasized …

The electrocardiogram in the diagnosis and management of patients with dilated cardiomyopathy

G Finocchiaro, M Merlo, N Sheikh… - … of Heart Failure, 2020 - Wiley Online Library
… manifest cardiac involvement with LV or biventricular systolic … CRT in symptomatic heart
failure patients (NYHA class ≥II) … 150 ms.64, 65 Although patients with LBBB are more likely to …

Cirrhotic cardiomyopathy

KT Yoon, H Liu, SS Lee - Current gastroenterology reports, 2020 - Springer
cardiac contractility is concentration- and time-dependent [16]. miRNA-130a improves cardiac
function in rats with noncirrhotic heart failurecardiac diastolic [48] and systolic function [50]…

Left ventricular post-infarct remodeling: implications for systolic function improvement and outcomes in the modern era

P van der Bijl, R Abou, L Goedemans, BJ Gersh… - Heart Failure, 2020 - jacc.org
… In summary, a similar evolution of LV systolic function improvement is seen in patients with
and without LV post-infarct remodeling. Although some determinants of both these processes …

CDR132L improves systolic and diastolic function in a large animal model of chronic heart failure

S Batkai, C Genschel, J Viereck, S Rump… - European heart …, 2021 - academic.oup.com
… in cardiac function and the reversal of adverse cardiac remodelling 2 months of post-MI in a
large animal model. The pleiotropic effects of cardiac … and the progression of heart failure, 3 …

Arrhythmogenic right ventricular cardiomyopathy: characterization of left ventricular phenotype and differential diagnosis with dilated cardiomyopathy

A Cipriani, B Bauce, M De Lazzari, I Rigato… - Journal of the …, 2020 - Am Heart Assoc
… In our age‐group of patients, an impaired LV systolic function was defined as an LVEF ≤0.48
for men and 0.50 for women. Regional wall motion abnormalities (WMA) were evaluated …

Effect of mavacamten on echocardiographic features in symptomatic patients with obstructive hypertrophic cardiomyopathy

SM Hegde, SJ Lester, SD Solomon, M Michels… - Journal of the American …, 2021 - jacc.org
… risk of disease progression, including heart failure, atrial fibrillation, and … functional cardiac
abnormalities, including LVOT gradient, degree of hypertrophy, systolic and diastolic function

[HTML][HTML] Myocardial work in nonobstructive hypertrophic cardiomyopathy: implications for outcome

YL Hiemstra, P van der Bijl, M El Mahdiui, JJ Bax… - Journal of the American …, 2020 - Elsevier
… , patients with HCM showed slightly higher systolic blood … patients with HCM (17%); 22
patients (20%) had heart failure … Heart Association functional class ≥ II), and 21 patients (19%…