DNA Adducts in Cancer Chemotherapy
Y Li - Journal of Medicinal Chemistry, 2024 - ACS Publications
… DNA adducts formed by the US FDA-approved drugs. Moreover, clinical studies on DNA
adducts … into the use of DNA adducts as biomarkers for guiding personalized cancer treatment. …
adducts … into the use of DNA adducts as biomarkers for guiding personalized cancer treatment. …
Detection of DNA adducts derived from the tobacco carcinogens, benzo[a]pyrene and dibenzo[def,p]chrysene in human oral buccal cells
KM Chen, YW Sun, NM Krebs, D Sun… - …, 2022 - academic.oup.com
… Consequently, DNA adducts are regarded as the most direct … DNA adducts derived from
B[a]P and DB[a,l]P in buccal cells … Head and neck squamous cell carcinoma (HNSCC) ranks as …
B[a]P and DB[a,l]P in buccal cells … Head and neck squamous cell carcinoma (HNSCC) ranks as …
DNA adducts: Formation, biological effects, and new biospecimens for mass spectrometric measurements in humans
B Hwa Yun, J Guo, M Bellamri… - Mass spectrometry …, 2020 - Wiley Online Library
… It is now possible to measure some DNA adducts in human … formation and biological effects
of DNA adducts, and highlight our advances … for carcinogen DNA adduct biomarker research. …
of DNA adducts, and highlight our advances … for carcinogen DNA adduct biomarker research. …
Lipid peroxidation: Reactive carbonyl species, protein/DNA adducts, and signaling switches in oxidative stress and cancer
NT Moldogazieva, SP Zavadskiy, DV Astakhov… - Biochemical and …, 2023 - Elsevier
… including protein and DNA adducts in biological samples [23]. … -modified protein and DNA
adducts in both physiological and … mechanisms of protein and DNA adduct formation. We …
adducts in both physiological and … mechanisms of protein and DNA adduct formation. We …
[HTML][HTML] … analysis revealed a reduction in the global level of C5-hydroxymethyl-2′-deoxycytidine in the non-tumoral upper urinary tract mucosa of urothelial carcinoma …
Y Matsushita, Y Iwashita, S Ohtsuka, I Ohnishi… - Genes and …, 2021 - Springer
… of DNA adducts in carcinogenesis in the urothelial system, we investigated 53 DNA adducts
… of patients with renal cell carcinoma, upper urinary tract urothelial carcinoma, and other …
… of patients with renal cell carcinoma, upper urinary tract urothelial carcinoma, and other …
[HTML][HTML] Mass spectrometric profiling of DNA adducts in the human stomach associated with damage from environmental factors
I Ohnishi, Y Iwashita, Y Matsushita, S Ohtsuka… - Genes and …, 2021 - Springer
… for these carcinogenic and irreversible mutations involve DNA adduct formation, which is the
… to DNA and form DNA adducts. Certain DNA adducts may impede accurate DNA replication …
… to DNA and form DNA adducts. Certain DNA adducts may impede accurate DNA replication …
… –Nanoelectrospray Ionization–High-Resolution Tandem Mass Spectrometry of Multiple DNA Adducts Related to Cigarette Smoking in Oral Cells in the Shanghai …
… (21) Acrolein administered by inhalation caused a significant increase in the incidence of
malignant lymphoma in female mice and rare rhabdomyoma and squamous cell carcinoma in …
malignant lymphoma in female mice and rare rhabdomyoma and squamous cell carcinoma in …
Quantitation of DNA adducts resulting from acrolein exposure and lipid peroxidation in oral cells of cigarette smokers from three racial/ethnic groups with differing risks …
SL Park, L Le Marchand, G Cheng… - Chemical research in …, 2022 - ACS Publications
… Thus, exposure to acrolein by inhalation significantly increased the incidence of malignant
lymphoma in female mice and caused rare rhabdomyoma and squamous cell carcinoma of …
lymphoma in female mice and caused rare rhabdomyoma and squamous cell carcinoma of …
New horizons of DNA adductome for exploring environmental causes of cancer
Y Totsuka, M Watanabe, Y Lin - Cancer science, 2021 - Wiley Online Library
… the DNA adducts are repaired by cellular processes, but the remaining, unrepaired adducts
can cause genomic mutations during DNA … DNA adducts listed in an in-house DNA adducts …
can cause genomic mutations during DNA … DNA adducts listed in an in-house DNA adducts …
[HTML][HTML] Geospatial assessments of DNA adducts in the human stomach: a model of field cancerization
Y Iwashita, I Ohnishi, Y Matsushita, S Ohtsuka… - Cancers, 2021 - mdpi.com
… The concept of field cancerization was proposed by Slaughter in 1953 [80], taking oral
squamous cell carcinoma as an example. The planes composing stratified squamous epithelium …
squamous cell carcinoma as an example. The planes composing stratified squamous epithelium …
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