DNA methylation dynamics in the female germline and maternal-effect mutations that disrupt genomic imprinting
… The blastocyst represents the stage at which the first cellular lineages have become apparent,
comprising the trophectoderm (TE), which gives rise to the extraembryonic tissues, and …
comprising the trophectoderm (TE), which gives rise to the extraembryonic tissues, and …
The DNA methylation landscape of advanced prostate cancer
… We next identified DNA methylation valleys (DMVs), broad regions of hypo-methylation
59,60 that are associated with either the activating histone mark H3K4me3 or the repressive …
59,60 that are associated with either the activating histone mark H3K4me3 or the repressive …
DNA methylation signatures of autoimmune diseases in human B lymphocytes
M Zouali - Clinical Immunology, 2021 - Elsevier
… of DNA methylation to shape events that impart generation of plasma cells and memory B
cells, … DNA methylation maps of five human B-cell lineage subpopulations, including pre-B-II …
cells, … DNA methylation maps of five human B-cell lineage subpopulations, including pre-B-II …
DNA methylation and histone variants in aging and cancer
A Mangelinck, C Mann - International Review of Cell and Molecular Biology, 2021 - Elsevier
… humans on modifications of DNA methylation and histone variants … DNA methylation
maintenance lead to global decreases in DNA methylation with relaxed repression of repeated DNA …
maintenance lead to global decreases in DNA methylation with relaxed repression of repeated DNA …
Phenotypic plasticity: what has DNA methylation got to do with it?
… Several insect lineages, including Diptera, some Lepidoptera, … DNA methylation patterns
cell by cell, we may miss the crucial cell type, and therefore miss crucial DNA methylation …
cell by cell, we may miss the crucial cell type, and therefore miss crucial DNA methylation …
Evolutionary history of DNA methylation related genes in chordates: new insights from multiple whole genome duplications
… DNA methylation is an important epigenetic mechanism … However, increased copy numbers
of DNA methylation related … the evolutionary history of DNA methylation genes in chordates. …
of DNA methylation related … the evolutionary history of DNA methylation genes in chordates. …
DNA methylation across the tree of life, from micro to macro-organism
… the DNA methylation is not that well-known, it plays a different role like other organisms. In
mammals, the DNA methylation … development and abnormal DNA methylation connected with …
mammals, the DNA methylation … development and abnormal DNA methylation connected with …
LSD1 and Aberrant DNA Methylation Mediate Persistence of Enteroendocrine Progenitors That Support BRAF-Mutant Colorectal Cancer
… datasets provides detailed insights into the differentiation of distinct intestinal cell lineages.
A, RNA velocity stream plots (top) and directed PAGA plots (bottom) of the colon, H508 EV, …
A, RNA velocity stream plots (top) and directed PAGA plots (bottom) of the colon, H508 EV, …
DNA methylation markers in the diagnosis and prognosis of common leukemias
H Jiang, Z Ou, Y He, M Yu, S Wu, G Li, J Zhu… - Signal transduction and …, 2020 - nature.com
… of lymphoid or myeloid lineage or from hematopoietic stem cells. The diagnosis of … DNA
methylation changes have been reported extensively in cancer studies. The methylation …
methylation changes have been reported extensively in cancer studies. The methylation …
Impact of DNA methylation on 3D genome structure
D Buitrago, M Labrador, JP Arcon, R Lema… - Nature …, 2021 - nature.com
… that lacks DNA methylation machinery making it a perfect model system to study the intrinsic
role of DNA methylation in chromatin structure and function. We expressed the murine DNA …
role of DNA methylation in chromatin structure and function. We expressed the murine DNA …