… cell differentiation among the different cell states seen in our scRNA-seq data. Relative to the
cNK cells… resulting in the ieILC1 state and another resulting in the NR4A2-expressing NK-2 …

… Head and neck cancer is no exception, and in this review, we use head and neck as a
case study for how partial-EMT (p-EMT) cell states may play an important role in cancer …

… cell response in cancer and chronic viral infections is T cell dysfunction, sometimes termed
exhaustion, a cell state … the importance of further interrogating the state of CD8 + TILs in HPV-…

… the complex biology underlying the state of the immune system within the tumor
microenvironment of HNSCC. Further insight into immune cell states will help identify features …

… cells [20]. A third study also implicated AXL in anti-EGFR resistance, but it was shown in
non-small cell lung cancer cells … The cancer stem cell (CSC) theory states that a tumor contains a …

… Of these cancers, squamous cell carcinoma of the head and neck accounts for over 90% of
… Committee on Cancer (AJCC) staging of head and neck cancer: rationale and implications. …

… cell states present in the tumour using pseudotime analyses. These analyses showed that
CD8 T cells that start from a stem-like state (… reaching a terminally differentiated state (cluster 3)…

… )-specific B cell responses are detectable in samples from patients with HPV-positive head
and neck cancers, … HPV-specific antibody secreting cells (ASCs) were present in the tumour …

… Using this data set, we observe an elastic sub-state of fibroblast differentiation and its … in
head and neck cancer 47 . Previously we have reported that PD-1 high CD8 + T cells contained …

… neck cancers are derived from the mucosal epithelium in the oral cavity, pharynx and larynx
and are known collectively as head and neck squamous cell … a persistent state of activation …