… cells) in age-related cardiovascular diseases. Then, we highlight the targets (SIRT1 and
mTOR) that regulating cellular senescence in cardiovascular disorders. Furthermore, we review …

… prevent and/or treat chronic cardiac disease and the safety of … role of cellular senescence
in cardiac disease potentially has … information linking cellular senescence to cardiac disease, …

The endothelium, a cellular monolayer lining the blood vessel wall, plays a critical role in
maintaining multiorgan health and homeostasis. Endothelial functions in health include …

… as a second messenger in cellular signaling. Through targeting … Cardiovascular diseases
are the leading cause of morbidity … the progression of various cardiovascular diseases, such as …

… Inflammation is an important process involved in several cardiovascular diseases (CVDs),
and nod-like receptor family pyrin domain containing 3 (NLRP3) inflammasome is a vital …

… In fact, without the identification of a specific and direct cellular target, it is very difficult to
evaluate their clinical relevance. An additional key issue regards “who does the job”, the …

… The complex pathobiology underlying cardiovascular diseases (CVDs) has yet to be … ,
diagnostic and prognostic biomarkers as well as drug targets in CVDs. To date, most of studies …

… Cardiovascular diseases comprise several disorders such as coronary artery diseases,
stroke, hypertension, heart failure, congenital heart diseases, and vascular diseases. The …

… coronary artery disease. In addition, a study conducted in 40 patients suffering from T2DM
with cardiovascular disease … with the prognosis of cardiovascular complications. In particular, …

… Endotheliocytes and platelets have been shown to be the major sources of EVs in patients
with stable coronary artery disease (CAD). Atherosclerotic conditions promote the packaging …