… The workshop sessions addressed key challenges in carcinogenicity assessment related
to … and assessing mechanisms and MoAs relevant to human cancers. At present, full …

… Further discussion of opportunities to advance the field of toxicogenomics and implement
near-term tools/solutions for contemporary challenges in cancer risk assessment follows below…

… available to assess non-genotoxic carcinogenicity (NGTxC). … group worked on the challenging
task of building consensus … and approaches to cancer hazard assessment. This thought-…

… cannot be conclusively assessed due to a lack of substance-specific carcinogenicity data.
In … Concern (TTC) concept may be used to assess the toxicological relevance of (unintended) …

… These challenges may be more easily overcome by the novel … Here, we propose an AOP for
lung cancer induced by … -based integrated assessment of lung carcinogenicity. The potential …

… ) discussing critical issues in cancer hazard assessments, and (c) … carcinogen; (b) by being
exposed to a human carcinogen at … in cancer risk (this apply only if the carcinogen follows the …

… bioassays have been long-required studies for regulatory assessment of human cancer hazard
… Another consideration in the ReCAAP framework, and one of the most challenging, is the …

… chemicals for risk assessment. Furthermore, we propose that … We propose that these
challenges highlight the need for … We contend that inclusion of a carcinogenic chemical(s) will …

… on the relation between DNA damage and cancer risk. Part B … Additionally, special attention
is given to some carcinogenic … for the assessment of the carcinogenic risk associated with …

… will enhance and accelerate carcinogen identification, a first step in cancer prevention. …
One important advantage of using the KCs to assemble data relevant to carcinogenic …