Immune checkpoint inhibitors in cancer therapy

Y Shiravand, F Khodadadi, SMA Kashani… - Current …, 2022 - mdpi.com
… medicine, and cancer therapeutics [1]. Immunotherapy such as adoptive cell transfer (ACT),
and immune checkpoint inhibitors (ICIs), is a type of cancer therapy, taking advantage of …

Immune checkpoint inhibitor‐based strategies for synergistic cancer therapy

M He, T Yang, Y Wang, M Wang, X Chen… - Advanced …, 2021 - Wiley Online Library
… of various immune checkpoint inhibitors are summarized, while the interactive mechanism
and recent progress of ICBT-based synergistic therapies with other immunotherapy, …

Multifaceted carbonized metal–organic frameworks synergize with immune checkpoint inhibitors for precision and augmented cuproptosis cancer therapy

C Zhao, X Tang, X Chen, Z Jiang - ACS nano, 2024 - ACS Publications
… Immune checkpoint inhibitors (ICIs) are a class of therapeutic agents that target the key
regulatory molecules governing the response of the immune system to cancer. (14−17) ICIs such …

A decade of immune-checkpoint inhibitors in cancer therapy

C Robert - Nature communications, 2020 - nature.com
… -PD1 drugs for the highly mutated cancers linked to a mismatch DNA repair deficiency (microsatellite
instability) 8 . This is a rare example in the history of cancer therapy that a drug was …

Combination therapy with immune checkpoint inhibitors (ICIs); a new frontier

S Vafaei, AO Zekiy, RA Khanamir, BA Zaman… - Cancer Cell …, 2022 - Springer
… As one of the most eminent eras in the context of tumor immunotherapy, immune-checkpoint
inhibitors (ICIs) have engendered remarkable therapeutic outcomes as a result of their …

Immune checkpoint inhibitors: a promising anticancer therapy

S Singh, D Hassan, HM Aldawsari, N Molugulu… - Drug discovery today, 2020 - Elsevier
… Significant milestones in the development of cancer immune checkpoint inhibitors. Abbreviations:
cd28, cluster of differentiation 28; CTLA-4, cytotoxic T lymphocyte-associated protein 4; …

[HTML][HTML] Autoimmune diseases and immune-checkpoint inhibitors for cancer therapy: review of the literature and personalized risk-based prevention strategy

J Haanen, MS Ernstoff, Y Wang, AM Menzies… - Annals of oncology, 2020 - Elsevier
… For this reason, we propose keeping anti-TNF-α inhibitors as the primary prevention
therapy in both AS and PsA. Upon the initial diagnosis of cancer, we recommend switching to …

[HTML][HTML] Challenges in lung cancer therapy during the COVID-19 pandemic

L Calabrò, S Peters, JC Soria… - The Lancet …, 2020 - ncbi.nlm.nih.gov
checkpoint inhibitor therapy—neither for treating physicians who want to avoid the overlapping
immune checkpoint inhibitor… are unsuitable for immune checkpoint inhibitor therapy. First, …

Checkpoint inhibitor therapy for metastatic triple-negative breast cancer

AL Heeke, AR Tan - Cancer and Metastasis Reviews, 2021 - Springer
… clinical development of checkpoint inhibitors in the treatment of metastatic TNBC will be
discussed, including clinical outcomes with monotherapy and combination therapy regimens, …

Tumor immunotherapies by immune checkpoint inhibitors (ICIs); the pros and cons

A Naimi, RN Mohammed, A Raji, S Chupradit… - Cell communication and …, 2022 - Springer
… axes, resulting in the evolution of immune checkpoint inhibitors (ICIs). Then, ICIs have … ICIs
based therapies can be practical and rational therapeutic approaches to treat cancer patients. …