[HTML][HTML] Aneuploidy and DNA methylation as mirrored features of early human embryo development
EN Tolmacheva, SA Vasilyev, IN Lebedev - Genes, 2020 - mdpi.com
… these stages is such that we can only guess what an imbalance of DNA methylation may
contribute to incorrect chromosome segregation at this stage—the hypomethylation of repetitive …
contribute to incorrect chromosome segregation at this stage—the hypomethylation of repetitive …
[HTML][HTML] DNA methylation-based sex classifier to predict sex and identify sex chromosome aneuploidy
… chromosomes, thousands of CpG sites on autosomes also show very different DNA methylation
patterns … co-variate, when undertaking methylation and phenotype association studies. …
patterns … co-variate, when undertaking methylation and phenotype association studies. …
Evaluation of genome-wide DNA methylation profile of human embryos with different developmental competences
M Yang, X Tao, K Scott, Y Zhan, RT Scott Jr… - Human …, 2021 - academic.oup.com
… between DNA methylation level and ploidy status (aneuploidy [n … the DNA methylation level
on the chromosome scale. … have lower methylation level on the involved chromosome while …
on the chromosome scale. … have lower methylation level on the involved chromosome while …
[HTML][HTML] Losing DNA methylation at repetitive elements and breaking bad
XG Pappalardo, V Barra - Epigenetics & chromatin, 2021 - Springer
… DNA methylation is an epigenetic … chromosome stability) by controlling both gene expression
and chromatin structure. Therefore, the onset of an incorrect pattern of DNA methylation is …
and chromatin structure. Therefore, the onset of an incorrect pattern of DNA methylation is …
Detection of aberrant DNA methylation patterns in sperm of male recurrent spontaneous abortion patients
RH Ma, ZG Zhang, YT Zhang, SY Jian, BY Li - Zygote, 2023 - cambridge.org
… Some evidence has suggested that the risk of aneuploidy embryos in the high DFI group
was 55% … Plus, DNA methylation can impact the stability of chromosomes, and chromosomal …
was 55% … Plus, DNA methylation can impact the stability of chromosomes, and chromosomal …
DNA methylation episignatures: insight into copy number variation
L der Laan, K Rooney, TMA Trooster… - …, 2022 - Taylor & Francis
… are limited in detection of smaller aberrations (<3 Mb) [Citation35] and are currently
primarily used for detection of whole chromosome aneuploidies or balanced rearrangements. …
primarily used for detection of whole chromosome aneuploidies or balanced rearrangements. …
Autosomal sex-associated co-methylated regions predict biological sex from DNA methylation
E Gatev, AM Inkster, GL Negri, C Konwar… - Nucleic Acids …, 2021 - academic.oup.com
… DNA methylation (DNAm) is a strong … chromosome aneuploidies (Klinefelter [47,XXY], Turner
[45,X] and 47,XXX syndrome) revealed an intimate relationship between sex chromosomes …
[45,X] and 47,XXX syndrome) revealed an intimate relationship between sex chromosomes …
Effects of aneuploidy on cell behaviour and function
… 21, which stimulates de novo DNA methylation 95 . Altered DNA methylation patterns were
… with various numbers of group 1 homologous chromosomes 96 . Remarkably, the altered …
… with various numbers of group 1 homologous chromosomes 96 . Remarkably, the altered …
LINE-1 retrotransposon methylation in chorionic villi of first trimester miscarriages with aneuploidy
SA Vasilyev, EN Tolmacheva, OY Vasilyeva… - Journal of Assisted …, 2021 - Springer
… in DNA methylation, and chromosome 15 has no genes annotated for DNA methylation in the
… This may explain why the level of LINE-1 methylation did not increase in miscarriages with …
… This may explain why the level of LINE-1 methylation did not increase in miscarriages with …
29. Increased micronuclei frequency and DNA methylation patterns associated with Down syndrome regression disorder
KA Rafferty, D Lapato, K Turner… - Cancer …, 2022 - cancergeneticsjournal.org
… We hypothesized that acquired somatic cell chromosomal instability and/or epigenetic … cell
chromosomal instability have been associated with stress and/or an aneuploidy chromosomal …
chromosomal instability have been associated with stress and/or an aneuploidy chromosomal …