[HTML][HTML] Selective phytochemicals targeting pancreatic stellate cells as new anti-fibrotic agents for chronic pancreatitis and pancreatic cancer

P Ramakrishnan, WM Loh, SCB Gopinath… - … Pharmaceutica Sinica B, 2020 - Elsevier
… Application of phytochemicals as new anti-fibrotic agents in treating chronic pancreatitis and
pancreatitis cancer In recent decades, plant-based/herbal constituents and natural products …

Natural compounds flavonoids as modulators of inflammasomes in chronic diseases

BA Owona, WA Abia, PF Moundipa - International immunopharmacology, 2020 - Elsevier
natural compounds to disease treatment has become a unique trend in clinical research.
Flavonoids, a group of polyphenolic compounds … and progression of chronic disorders including …

Drug discovery and formulation development for acute pancreatitis

X Jiang, YW Zheng, S Bao, H Zhang, R Chen… - Drug Delivery, 2020 - Taylor & Francis
… have been reported to be effective against pancreatitis (Sun et al., Citation… natural derived
bioactive compounds that have been demonstrated to be effective against acute pancreatitis in …

Isoliquiritigenin ameliorates caerulein‐induced chronic pancreatitis by inhibiting the activation of PSCs and pancreatic infiltration of macrophages

LJ Wang, L He, L Hao, HL Guo, XP Zeng… - Journal of Cellular …, 2020 - Wiley Online Library
… -type dietary compound derived from licorice, on pancreatic fibrosis and inflammation in a …
pancreatic fibrosis and infiltration of macrophages. Further in vitro studies in human pancreatic

Protective and therapeutic effects of natural products against diabetes mellitus via regenerating pancreatic β‐cells and restoring their dysfunction

DK Semwal, A Kumar, S Aswal… - Phytotherapy …, 2021 - Wiley Online Library
… Different natural compounds such as flavonoid and alkaloids have proven to exhibit … by
increasing pancreatic β-cell regeneration. Similarly, quercetin, a common natural flavonoid, …

[HTML][HTML] Resveratrol supplementation and acute pancreatitis: A comprehensive review

S Agah, A Akbari, E Sadeghi, M Morvaridzadeh… - Biomedicine & …, 2021 - Elsevier
… For instance, severe AP can alter the function and structure of the pancreatic duct and
eventually cause chronic obstructive pancreatitis [5]. Current state-of-the-art care of AP mainly …

[HTML][HTML] Chaiqin chengqi decoction alleviates severity of acute pancreatitis via inhibition of TLR4 and NLRP3 inflammasome: identification of bioactive ingredients via …

Y Wen, C Han, T Liu, R Wang, W Cai, J Yang, G Liang… - Phytomedicine, 2020 - Elsevier
… The detailed information of reagents, natural compound standards and quantitative
reverse transcription polymerase chain reaction (RT-qPCR) primer pairs are provided in the …

[HTML][HTML] Cyclodextrins, natural compounds, and plant bioactives—a nutritional perspective

S Wüpper, K Lüersen, G Rimbach - Biomolecules, 2021 - mdpi.com
… Accordingly, we present studies where the complexation of natural compounds such as …
from increased bioavailability of plant extracts or natural compounds owing to CD complexation. …

Pyroptosis in acute pancreatitis and its therapeutic regulation

A Al Mamun, SA Suchi, MA Aziz, M Zaeem, F Munir… - Apoptosis, 2022 - Springer
… Moreover, we briefly present some experimental compounds targeting pyroptosis-regulated
cell death for exploring novel therapeutic directions for the treatment and management of AP…

Dihydrokaempferol (DHK) ameliorates severe acute pancreatitis (SAP) via Keap1/Nrf2 pathway

X Liang, C Hu, C Liu, K Yu, J Zhang, Y Jia - Life Sciences, 2020 - Elsevier
… Dihydrokaempferol (DHK) (CAS Number: 480-20-6) is a type of flavonoid, which is a natural
compound extracted from a Traditional Chinese medicinal plant Bauhinia championii (Benth)…