… β-lactamase, PDC-8 in CLB 24388 and PDC-19a in isolate EM 2972704. These PDC β-lactamases …
resistance, we propose that the PDC β-lactamases in these isolates serve to bind the …

… faecalis clinical isolates … of β-lactams and, specifically, of BPR; 3) to compare the pbp4
expression levels in all E. faecalis clinical isolates with reduced susceptibility to beta-lactams and …

… for 1,445 Pseudomonas aeruginosa clinical isolates and a large panel of isogenic mutants
showing the most relevant mutation-driven β-lactam resistance mechanisms. Imipenem-…

… of 119 extended-spectrum β-lactamase (ESBL)-producing Enterobacterales and 60 β-lactam-resistant
Pseudomonas aeruginosa clinical isolates collected from three US institutions. …

… With the widespread usage of gene sequencing to identify β-lactamase genes in clinical
isolates, multiple variants of the common TEM and SHV enzymes have been identified. As of …

… β-lactamases (ESBLs) [7]. ATM is effective against MBL-producer infections as long as these
isolates … , are commonly used in clinical practice in association with β-lactams. However, …

… In the present study, the in vitro activity of the combinations of cefepime with taniborbactam
and meropenem with taniborbactam against MBL-producing clinical isolates were compared …

… the 13 β-lactam combinations against a library of 21 clinical isolates obtained from CF patients
in recent years. The rationale for including these specific dual-β-lactam combinations is a …

… β-lactamase genotyping approach was employed to dissect the molecular basis for 3GC
resistance in 7168 clinical isolates of … of important β-lactam and β-lactam/β-lactamase inhibitor …

This study aimed to investigate the molecular mechanisms of carbapenem and colistin
resistance in K. pneumoniae and E. coli isolates obtained from hospitalized patients in …