[HTML][HTML] Comparative clinical outcomes for patients with advanced NSCLC harboring EGFR exon 20 insertion mutations and common EGFR mutations
… Real-world clinical outcomes in patients with advanced NSCLC harboring EGFR exon 20
insertion (… We conducted a retrospective cohort study to assess the clinical outcomes of EGFR …
insertion (… We conducted a retrospective cohort study to assess the clinical outcomes of EGFR …
[HTML][HTML] Molecular characteristics and clinical outcomes of EGFR exon 19 c-helix deletion in non–small cell lung cancer and response to EGFR TKIs
C Xu, L Lei, W Wang, L Lin, Y Zhu, H Wang, L Miao… - Translational …, 2020 - Elsevier
Epidermal growth factor receptor (EGFR) exon 19 deletion (E19del) is the most common
activating mutation in advanced non–small cell lung cancer (NSCLC) and associates with the …
activating mutation in advanced non–small cell lung cancer (NSCLC) and associates with the …
[HTML][HTML] Uncommon EGFR mutations in non-small-cell lung cancer: A systematic literature review of prevalence and clinical outcomes
T John, A Taylor, H Wang, C Eichinger, C Freeman… - Cancer …, 2022 - Elsevier
… reported these outcomes either for common versus uncommon mutations, or for exon 20 …
Clinical outcomes for individuals with mutations in exon 20 (excluding T790M) were an area …
Clinical outcomes for individuals with mutations in exon 20 (excluding T790M) were an area …
Characterization of MET exon 14 alteration and association with clinical outcomes of crizotinib in Chinese lung cancers
H Yang, Z Zhou, L Lin, M Yang, C Li, Z Li, X Yu… - Lung Cancer, 2020 - Elsevier
… exon 14 alterations involving either splice acceptor or donor sites had similar clinical
outcomes… In addition, we report the first clinical evidence of a patient with lung adenocarcinoma …
outcomes… In addition, we report the first clinical evidence of a patient with lung adenocarcinoma …
Non-small cell lung cancer with EGFR exon 20 insertion mutation: a systematic literature review and meta-analysis of patient outcomes
CS Kwon, HM Lin, V Crossland… - … medical research and …, 2022 - Taylor & Francis
… (RWE) studies reporting clinical outcomes for EGFR exon 20 insertion mutation-positive …
outcomes for the overall group of exon 20 insertions and either did not report outcomes for …
outcomes for the overall group of exon 20 insertions and either did not report outcomes for …
[HTML][HTML] Epidemiological and clinical burden of EGFR Exon 20 insertion in advanced non-small cell lung cancer: A systematic literature review
H Burnett, H Emich, C Carroll, N Stapleton… - PLoS …, 2021 - journals.plos.org
… of Exon 20ins, 2) the prognostic impact of Exon 20ins … and Exon 20ins, 3) treatment
patterns and clinical outcomes in … study in which patients received either erlotinib or gefitinib …
patterns and clinical outcomes in … study in which patients received either erlotinib or gefitinib …
A Real-World Study of Patients with Advanced Non-squamous Non-small Cell Lung Cancer with EGFR Exon 20 Insertion: Clinical Characteristics and Outcomes
C Chouaid, T Filleron, D Debieuvre, M Pérol, N Girard… - Targeted …, 2021 - Springer
… patterns, and clinical outcomes were assessed for patients harboring EGFR exon 20ins, …
not appear to be an attractive option in this population either [19]. In Europe, no targeted …
not appear to be an attractive option in this population either [19]. In Europe, no targeted …
Response to Standard Therapies and Comprehensive Genomic Analysis for Patients with Lung Adenocarcinoma with EGFR Exon 20 Insertions
NJ Choudhury, AJ Schoenfeld, J Flynn, CJ Falcon… - Clinical Cancer …, 2021 - AACR
… We sought to describe the clinical outcomes and response to … evaluated their clinical outcomes
compared with a historical … somatic alterations associated with either cohort that met our …
compared with a historical … somatic alterations associated with either cohort that met our …
Treatment outcomes and safety of mobocertinib in platinum-pretreated patients with EGFR exon 20 insertion–positive metastatic non–small cell lung cancer: a phase 1 …
C Zhou, SS Ramalingam, TM Kim, SW Kim… - JAMA …, 2021 - jamanetwork.com
… Patients with active brain metastases (ie, either previously untreated or previously treated
with documented progression following treatment) were excluded. Patients with brain …
with documented progression following treatment) were excluded. Patients with brain …
EGFR exon 20 insertion mutations in Chinese advanced non-small cell lung cancer patients: molecular heterogeneity and treatment outcome from nationwide real …
G Yang, J Li, H Xu, Y Yang, L Yang, F Xu, B Xia… - Lung Cancer, 2020 - Elsevier
… growth factor receptor (EGFR) exon 20 insertion (ex20ins) … limited information on the clinical
outcome of these patients … either by polymerase chain reaction (PCR) for exon 18–21 or …
outcome of these patients … either by polymerase chain reaction (PCR) for exon 18–21 or …
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