The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy
D Bruni, HK Angell, J Galon - Nature Reviews Cancer, 2020 - nature.com
… , as well as patient outcome, are estimated on the basis of this staging system for a variety
of cancers 1,2,3 . However, significant differences in clinical outcome are observed in patients …
of cancers 1,2,3 . However, significant differences in clinical outcome are observed in patients …
[HTML][HTML] m6A RNA Methylation Regulator YTHDF1 Correlated With Immune Microenvironment Predicts Clinical Outcomes and Therapeutic Efficacy in Breast Cancer
Y Hu, Q Pan, M Wang, X Ai, Y Yan, Y Tian… - Frontiers in …, 2021 - frontiersin.org
… To determine the clinical implications of 13 m 6 A regulatory mRNAs in breast cancer, this …
6 A regulatory mRNAs and patients' clinical outcomes. Our results showed that the expression …
6 A regulatory mRNAs and patients' clinical outcomes. Our results showed that the expression …
[HTML][HTML] The current treatment paradigm for pancreatic ductal adenocarcinoma and barriers to therapeutic efficacy
DR Principe, PW Underwood, M Korc… - Frontiers in …, 2021 - frontiersin.org
… therapies are less efficacious but still carry the same risk of serious adverse effects, and
clinical outcomes … Here we discuss the current state of pancreatic cancer therapy, both surgical …
clinical outcomes … Here we discuss the current state of pancreatic cancer therapy, both surgical …
Effect of antithrombotic therapy on clinical outcomes in outpatients with clinically stable symptomatic COVID-19: the ACTIV-4B randomized clinical trial
… Among symptomatic clinically stable outpatients with COVID-19, treatment with aspirin or
apixaban compared with placebo did not reduce the rate of a composite clinical outcome. …
apixaban compared with placebo did not reduce the rate of a composite clinical outcome. …
Metastasis-directed therapy prolongs efficacy of systemic therapy and improves clinical outcomes in oligoprogressive castration-resistant prostate cancer
… from therapy. The number of metastases at progression was associated with clinical outcomes
… disease might benefit most from local therapy, and thus advanced imaging techniques as …
… disease might benefit most from local therapy, and thus advanced imaging techniques as …
Clinical efficacy and safety outcomes of bempedoic acid for LDL-C lowering therapy in patients at high cardiovascular risk: a systematic review and meta-analysis
Y Lin, C Parco, A Karathanos, T Krieger, V Schulze… - BMJ open, 2022 - bmjopen.bmj.com
… to assess efficacy and safety for clinical outcomes in high … on BAs efficacy in improving
relevant clinical outcomes, which … relevant impact on major clinical outcomes. Primarily, duration …
relevant clinical outcomes, which … relevant impact on major clinical outcomes. Primarily, duration …
[HTML][HTML] Real-world efficacy of regdanvimab on clinical outcomes in patients with mild to moderate COVID-19
T Kim, DH Joo, SW Lee, J Lee, SJ Lee… - Journal of Clinical …, 2022 - mdpi.com
… Although the proportion of patients with disease progression was slightly lower in the present
study, the difference could be attributed to the heterogeneity in defining clinical outcomes …
study, the difference could be attributed to the heterogeneity in defining clinical outcomes …
[HTML][HTML] Real-world efficacy data and predictive clinical parameters for treatment outcomes in advanced esophageal squamous cell carcinoma treated with immune …
… the efficacy outcomes in our study, even though it was limited by the small sample size.
Therefore, the current study focused on clinical … with a poor clinical outcome for various cancers …
Therefore, the current study focused on clinical … with a poor clinical outcome for various cancers …
[HTML][HTML] Association of convalescent plasma treatment with clinical outcomes in patients with COVID-19: a systematic review and meta-analysis
… clinical outcomes. But it doesn't reply to the question of its utility if it is used according to
what now is considered an appropriate treatment. Two requirements seem to be essential for …
what now is considered an appropriate treatment. Two requirements seem to be essential for …
[HTML][HTML] Factors that influence clinical efficacy of live biotherapeutic products
B Pot, Y Vandenplas - European Journal of Medical Research, 2021 - Springer
… the clinical outcome. According to the limited data available, a dairy matrix often seems to
offer the best survival conditions. This may have an impact in individuals on milk-free diets [45]. …
offer the best survival conditions. This may have an impact in individuals on milk-free diets [45]. …
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