[HTML][HTML] Core proteome mediated therapeutic target mining and multi-epitope vaccine design for Helicobacter pylori
… this has been used for drug target mining in many pathogens like … genomics approach was
used to identify novel, essential, and human non-homologous drug as well as vaccine targets …
used to identify novel, essential, and human non-homologous drug as well as vaccine targets …
[HTML][HTML] Integrated core proteomics, subtractive proteomics, and immunoinformatics investigation to unveil a potential multi-epitope vaccine against schistosomiasis
… The pipeline revealed two antigenic proteins—calcium binding and mycosubtilin synthase
subunit C—as promising vaccine targets. T and B cell epitopes from the targeted proteins …
subunit C—as promising vaccine targets. T and B cell epitopes from the targeted proteins …
[HTML][HTML] … of Putative Vaccine and Drug Targets against the Methicillin-Resistant Staphylococcus aureus by Reverse Vaccinology and Subtractive Genomics …
… vaccine candidates and drug target proteins against the 16 strains of MRSA using reverse
vaccinology and subtractive genomics … The essential core proteome that has homology among …
vaccinology and subtractive genomics … The essential core proteome that has homology among …
[HTML][HTML] Chimeric vaccine designs against Acinetobacter baumannii using pan genome and reverse vaccinology approaches
… In this study the in-house pipeline PanRV was used to filter out the core genome targets
along with separate sequential filtering to double check the ambiguous results. The …
along with separate sequential filtering to double check the ambiguous results. The …
[HTML][HTML] Coronavirus pandemic—therapy and vaccines
K Lundstrom - Biomedicines, 2020 - mdpi.com
… genomic composition of SARS-CoV-2 and its lifecycle to identify potential drug and vaccine
targets… heat-labile enterotoxin B (LTB) and the core neutralizing epitope (COE) of PEDV was …
targets… heat-labile enterotoxin B (LTB) and the core neutralizing epitope (COE) of PEDV was …
[HTML][HTML] In silico functional prediction of hypothetical proteins from the core genome of Corynebacterium pseudotuberculosis biovar ovis
… targets, specially to investigate the role of these products in vitro, as well as their potential
to be involved in pathogenesis and its use for the development of new therapeutic targets …
to be involved in pathogenesis and its use for the development of new therapeutic targets …
[HTML][HTML] Vaccinomics to Design a Multi-Epitopes Vaccine for Acinetobacter baumannii
… proteins are not part of the core genome and are poor immunological targets [33]. On the
other hand, non-redundant proteins are good vaccine candidates because they are present in …
other hand, non-redundant proteins are good vaccine candidates because they are present in …
Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines
… These general design principles and nanoparticle platforms can, in principle, be applied
to a wide range of vaccine targets including HCV. Epitope scaffolds have been designed for …
to a wide range of vaccine targets including HCV. Epitope scaffolds have been designed for …
Immunoinformatics and vaccine development: an overview
AN Oli, WO Obialor, MO Ifeanyichukwu… - ImmunoTargets and …, 2020 - Taylor & Francis
… genomes for possible vaccine target. With these tools, many proteins of virulence interest can
be sequenced and the most essential gene of interest modeled for a potential vaccine … core …
be sequenced and the most essential gene of interest modeled for a potential vaccine … core …
Current status of pan-genome analysis for pathogenic bacteria
… Core genome is a set of gene families that are shared by all genomes of a target clade, which
… for possible discovery and development of vaccines and new drugs. Taken together, pan-…
… for possible discovery and development of vaccines and new drugs. Taken together, pan-…
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