[HTML][HTML] Adaptation to iron deficiency in human pathogenic fungi
MT Martínez-Pastor, S Puig - … et Biophysica Acta (BBA)-Molecular Cell …, 2020 - Elsevier
… Cryptococcus neoformans is another opportunistic pathogen that causes chronic pulmonary
infections and cryptococcosis, … under iron deprivation or in media with hemin as the sole iron …
infections and cryptococcosis, … under iron deprivation or in media with hemin as the sole iron …
… cytoplasmic heme sensor illuminates the impacts of mitochondrial and vacuolar functions and oxidative stress on heme-iron homeostasis in Cryptococcus neoformans
G Bairwa, E Sánchez-León, E Do, WH Jung… - Mbio, 2020 - Am Soc Microbiol
… Pathogens must compete with hosts to acquire sufficient iron for proliferation during
pathogenesis. The pathogenic fungus Cryptococcus neoformans is capable of acquiring iron from …
pathogenesis. The pathogenic fungus Cryptococcus neoformans is capable of acquiring iron from …
Regulatory and pathogenic mechanisms in response to iron deficiency and excess in fungi
J Pijuan, DF Moreno, G Yahya, M Moisa… - Microbial …, 2023 - Wiley Online Library
… iron-related virulence factors have the most common fungal human pathogens (Aspergillus
fumigatus, Cryptococcus neoformans… synergistic effect with iron deprivation in slowing growth …
fumigatus, Cryptococcus neoformans… synergistic effect with iron deprivation in slowing growth …
Coordinated regulation of iron metabolism in Cryptococcus neoformans by GATA and CCAAT transcription factors: connections with virulence
WH Jung, E Sánchez-León, JW Kronstad - Current genetics, 2021 - Springer
… that governing iron transport upon iron deprivation is a key role of the protein in C. … role
in regulating the response to iron deprivation compared to iron sufficiency. The ChIP-Seq and …
in regulating the response to iron deprivation compared to iron sufficiency. The ChIP-Seq and …
Metals and the cell surface of Cryptococcus neoformans
P Xue, G Hu, WH Jung, JW Kronstad - Current Opinion in Microbiology, 2023 - Elsevier
… host immune response and influencing phagocytosis, and capsule elaboration is regulated
by a number of host-related conditions including iron deprivation 7, 8. Effective therapy for …
by a number of host-related conditions including iron deprivation 7, 8. Effective therapy for …
A Transcriptional Regulatory Map of Iron Homeostasis Reveals a New Control Circuit for Capsule Formation in Cryptococcus neoformans
E Do, YJ Cho, D Kim, JW Kronstad, WH Jung - Genetics, 2020 - academic.oup.com
… human fungal pathogen Cryptococcus neoformans within the vertebrate host, and iron
sensing … In addition, upon iron deprivation, the CBC represses the expression of the GATA-type …
sensing … In addition, upon iron deprivation, the CBC represses the expression of the GATA-type …
[HTML][HTML] Involvement of Mrs3/4 in mitochondrial iron transport and metabolism in Cryptococcus Neoformans
Y Choi, E Do, G Hu, M Caza… - … of microbiology and …, 2020 - ncbi.nlm.nih.gov
… Cryptococcus neoformans is a pathogenic fungus that infects humans to cause … iron
accumulation in mitochondria, and that iron deprivation within mitochondria induced …
accumulation in mitochondria, and that iron deprivation within mitochondria induced …
The interplay between electron transport chain function and iron regulatory factors influences melanin formation in Cryptococcus neoformans
P Xue, E Sánchez-León, G Hu, CWJ Lee, B Black… - Msphere, 2024 - Am Soc Microbiol
… Connections between factors that regulate iron homeostasis … In this study, we identified
connections between iron … factor in the pathogenic fungus Cryptococcus neoformans. This fungus …
connections between iron … factor in the pathogenic fungus Cryptococcus neoformans. This fungus …
The “Little Iron Waltz”: The Ternary Response of Paracoccidioides spp. to Iron Deprivation
AF de Souza, MS de Paula, RM Lima, MG Silva… - Journal of Fungi, 2020 - mdpi.com
… mechanisms for iron uptake [9,15]. … iron deprivation by three main events: (1) the reductive
iron assimilation pathway (as described for Cryptococcus neoformans); (2) exploration of iron-…
iron assimilation pathway (as described for Cryptococcus neoformans); (2) exploration of iron-…
Vam6/Vps39/TRAP1‐domain proteins influence vacuolar morphology, iron acquisition and virulence in Cryptococcus neoformans
G Hu, E Bakkeren, M Caza… - Cellular …, 2021 - Wiley Online Library
… In this yeast, iron deprivation results in sorting of the proteins back to the plasma membrane
and iron addition causes targeting to the vacuole for degradation via the ESCRT protein-…
and iron addition causes targeting to the vacuole for degradation via the ESCRT protein-…
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