… The P2X7R upregulation has been shown to enhance inflammasome activation, which
leads to the release of proinflammatory cytokines and retinal degenerative diseases [86]. …

… Under IL-17A stimulation, miR-873 participates in inflammatory cytokine production in
astrocytes through the A20/NF-KB pathway in EAE mice (Liu X. et al., 2014; Shan et al., 2017; Liu X…

… ALS is a degenerative disease leading to the dysfunction of … production [95]. In addition,
IDO-activated cells can alter the cytokine production of APCs to anti-inflammatory cytokines, TGF-…

… OA is a progressive degenerative disease involving the entire joint structure in a vicious …
modulating immune cell proliferation and cytokine production. Interestingly, some immune cells …

… -mediated neuronal degeneration under pathological conditions. In … inhibiting the production
of pro-inflammatory cytokines, as … neurodegeneration and cytokines produced by activated …

… MSCs produce a number of substances, such as cytokines, … In addition, MSCs produce
a number of cytokines, including … Their activation leads to an increase in IL-6 production by …

… 1 hastens neuronal degeneration by increasing the production of IL-6 and the … cytokines in
the favor of pro-inflammatory cytokines leads to a cycle of further cytokine production, cytokine …

… includes an increased production of pro-inflammatory cytokines, a reduced activity of Treg
… Interestingly, IL1β and IL-6 production was increased, whereas that of IL-10 was reduced in …

… cytokines from systematic inflammation can also induce as much worse as from neurological
diseases or … of BBB, the main cytokines including IL-1β, TNFα, IL-6, and their mechanism on …

… by producing inflammatory cytokines such as TNF-α, IL-6, IL-1β, … degeneration significantly
compromises the brain [84,85]. … pro-inflammatory cytokine production and lessens microglia …