Anti-inflammatory therapy for atherosclerosis: focusing on cytokines

AV Poznyak, D Bharadwaj, G Prasad… - International journal of …, 2021 - mdpi.com
Cytokine-induced … Cytokines also stimulate migration, proliferation, and growth of SMCs,
affecting their functions. At the late stages of atherosclerosis, proinflammatory cytokines lead to …

Inflammatory cytokines and atherosclerotic plaque progression. Therapeutic implications

AV Sterpetti - Current Atherosclerosis Reports, 2020 - Springer
cytokines is generally related to the local pro-inflammatory stimuli. Many gene mutations
associated with atherosclerosiscytokines and more aggressive forms of atherosclerosis [22]. …

Inflammation in atherosclerosis—no longer a theory

P Libby - Clinical chemistry, 2021 - academic.oup.com
… as a signature cytokine interferon-gamma (IFN-γ), operate during atherosclerosis as disclosed
by the expression of Class II major histocompatibility antigens that this cytokine regulates. …

Atherosclerosis: orchestrating cells and biomolecules involved in its activation and inhibition

A Munjal, R Khandia - Advances in protein chemistry and structural biology, 2020 - Elsevier
… T REG suppress effector T cells in atherosclerosis through cytokines IL-10 and TGF-β. In
amice model production of IL-10 decreases the inflammation and plaque size in ApoE −/− mice. …

Inflammatory chemokines in atherosclerosis

S Gencer, BR Evans, EPC van der Vorst, Y Döring… - Cells, 2021 - mdpi.com
… Complications of atherosclerosis can become severe and lead to … great attention in the
research of atherosclerosis as they play a key … of atherosclerosis and their potential for targeting. …

Adipokines, adiposity, and atherosclerosis

L Liu, Z Shi, X Ji, W Zhang, J Luan, T Zahr… - Cellular and Molecular …, 2022 - Springer
atherosclerosis, while other adipokines, such as leptin, chemerin, resistin, and pro-inflammatory
cytokines … catalog the roles they play in atherosclerosis, and further explore adipokines …

Cytokines as therapeutic targets for cardio-and cerebrovascular diseases

L Liberale, S Ministrini, F Carbone, GG Camici… - Basic Research in …, 2021 - Springer
… the modulatory role of cytokines on atherosclerosis, myocardial infarction, and stroke.
Then, we discuss evidence from clinical trials specifically targeting cytokines and the potential …

The role of macrophages in the pathogenesis of atherosclerosis

AV Blagov, AM Markin, AI Bogatyreva, TV Tolstik… - Cells, 2023 - mdpi.com
… in atherosclerosis. In the current review, the significance of different phenotypes of macrophages
in the progression or regression of atherosclerosis … as a result of cytokine production. In …

The Role of miRNA‐146a and Proinflammatory Cytokines in Carotid Atherosclerosis

P Huang, X He, M Xu - BioMed Research International, 2020 - Wiley Online Library
The aim of this study was to investigate the expression and significance of miRNA‐146a in
peripheral blood of patients with carotid atherosclerosis (CAS). Patients with CAS were …

Inflammation and atherosclerosis: signaling pathways and therapeutic intervention

P Kong, ZY Cui, XF Huang, DD Zhang… - Signal transduction and …, 2022 - nature.com
… represents the transformation of inflammation in atherosclerosis from theory to practice. … in
the treatment of atherosclerosis, including inhibiting pro-inflammatory cytokines, blocking key …