Heterogeneity of T cells in atherosclerosis defined by single-cell RNA-sequencing and cytometry by time of flight
… disease, it is now established that atherosclerosis is a partial … response with proinflammatory
cytokine secretion. Recent … Here, we discuss T-cell heterogeneity in atherosclerosis with …
cytokine secretion. Recent … Here, we discuss T-cell heterogeneity in atherosclerosis with …
Pyroptosis is a critical immune-inflammatory response involved in atherosclerosis
X He, X Fan, B Bai, N Lu, S Zhang, L Zhang - Pharmacological Research, 2021 - Elsevier
… the secretion of inflammatory cytokines (IL-1β and IL-18). Atherosclerosis-related risk factors,
… can induce plaque instability and accelerate atherosclerosis progression. In this review, we …
… can induce plaque instability and accelerate atherosclerosis progression. In this review, we …
[HTML][HTML] Renin-angiotensin system in pathogenesis of atherosclerosis and treatment of CVD
AV Poznyak, D Bharadwaj, G Prasad… - International Journal of …, 2021 - mdpi.com
… of RAAS can be promising targets for atherosclerosis treatment. In this review, we also
summarize the data on treatment approaches involving cytokine targeting in CVD, which can …
summarize the data on treatment approaches involving cytokine targeting in CVD, which can …
[HTML][HTML] Inosine, an endogenous purine nucleoside, avoids early stages of atherosclerosis development associated to eNOS activation and p38 MAPK/NF-kB …
GF Lima, R de Oliveira Lopes, ABA Mendes… - European journal of …, 2020 - Elsevier
… increase in lipid levels and inflammatory cytokines production, while inosine treatment strongly
… as a potential drug for the treatment of cardiovascular disorders such as atherosclerosis. …
… as a potential drug for the treatment of cardiovascular disorders such as atherosclerosis. …
Macrophages in atherosclerosis regression
TJ Barrett - Arteriosclerosis, thrombosis, and vascular biology, 2020 - Am Heart Assoc
… Additionally, the treatment of Ldlr −/− mice with the M2-polarizing cytokine IL-13 inhibits
atherosclerosis progression, in part by its ability to skew plaque macrophage phenotype towards …
atherosclerosis progression, in part by its ability to skew plaque macrophage phenotype towards …
[HTML][HTML] The Role of Inflammation in Atherosclerosis: A Comprehensive Review of Mechanisms and Therapeutic Targets
O Elsaka - JOURNAL OF INDIAN COLLEGE OF CARDIOLOGY, 2024 - journals.lww.com
… In this review, we examine the evolving importance of inflammation in atherosclerosis, the …
Atherosclerosis is no longer solely a story of cholesterol, as inflammation fueled by cytokines …
Atherosclerosis is no longer solely a story of cholesterol, as inflammation fueled by cytokines …
[HTML][HTML] Modeling early stage atherosclerosis in a primary human vascular microphysiological system
X Zhang, M Bishawi, G Zhang, V Prasad… - Nature …, 2020 - nature.com
… To model the early stages of atherosclerosis in the TEBV system and identify the contribution
of a pro-inflammatory cytokine in early atherosclerosis development, TEBVs were exposed …
of a pro-inflammatory cytokine in early atherosclerosis development, TEBVs were exposed …
Calycosin action against atherosclerosis: integrating network pharmacology and in-silico investigation
H Xu, K Wu, C Guo, G Zhong - Acta Cardiologica, 2024 - Taylor & Francis
… of inflammatory response (positive regulation of cytokine production), response to oxidative
… curing atherosclerosis. Anti-inflammatory stress by reducing excessive cytokines and …
… curing atherosclerosis. Anti-inflammatory stress by reducing excessive cytokines and …
Empagliflozin inhibits macrophage inflammation through AMPK signaling pathway and plays an anti-atherosclerosis role
J Fu, H Xu, F Wu, Q Tu, X Dong, H Xie, Z Cao - International Journal of …, 2022 - Elsevier
… of empagliflozin on serum inflammatory cytokines, we detected the levels of inflammatory
cytokines in the serum of mice,and found that the levels of the inflammatory cytokines IL-6 and …
cytokines in the serum of mice,and found that the levels of the inflammatory cytokines IL-6 and …
[HTML][HTML] Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis
… of the NLRP3 inflammasome and pro-inflammatory cytokine production, which exacerbate
the chronic inflammatory state in atherosclerosis 34 . Accordingly, suppression of cholesterol …
the chronic inflammatory state in atherosclerosis 34 . Accordingly, suppression of cholesterol …