In utero treatment of congenital cytomegalovirus infection with valganciclovir: an observational study on safety and effectiveness

N Bourgon, R Lopez, J Fourgeaud… - Journal of …, 2024 - academic.oup.com
… In conclusion, our results suggest that valganciclovir treatment of infected fetuses is not
associated with maternal, fetal or neonatal side effects and demonstrated at least partial viral …

Role of valganciclovir in children with congenital CMV infection: a review of the literature

D Pata, D Buonsenso, A Turriziani-Colonna, G Salerno… - Children, 2023 - mdpi.com
… for congenital CMV infections. Currently, two different antivirals are in use: oral valganciclovir
(VGC) and … The aim of our study was to analyze the available data on the VGC treatment of …

Congenital cytomegalovirus infection: update on diagnosis and treatment

G Chiopris, P Veronese, F Cusenza, M Procaccianti… - Microorganisms, 2020 - mdpi.com
… In the case of symptomatic cCMV, we actually recommend treatment with oral valganciclovir
Valganciclovir is reserved for congenitally-infected neonates with the symptomatic disease …

Efficacy, safety, and pharmacokinetics of oral valganciclovir in patients with congenital cytomegalovirus infection

E Suganuma, H Sakata, N Adachi, S Asanuma… - Journal of Infection and …, 2021 - Elsevier
cytomegalovirus infection at our hospital during the study period, 36 patients (47%) received
antiviral treatment. Of … Since one patient who had completed treatment with VGCV before …

[HTML][HTML] Treatment with valacyclovir during pregnancy for prevention of congenital cytomegalovirus infection: a real-life multicenter Italian observational study

L Zammarchi, LR Tomasoni, G Liuzzi… - American Journal of …, 2023 - Elsevier
… on cytomegalovirus infection in pregnancy evaluating the effect of the introduction of
valacyclovir in the clinical practice for the prevention of vertical transmission of cytomegalovirus. …

Treatment for First Cytomegalovirus Infection Post–Hematopoietic Cell Transplant in the AURORA Trial: A Multicenter, Double-Blind, Randomized, Phase 3 Trial …

GA Papanicolaou, RK Avery… - Clinical Infectious …, 2024 - academic.oup.com
… of valganciclovir treatment for cytomegalovirus (CMV) infection … with fewer treatment-limiting
toxicities than valganciclovir. … , patients with first asymptomatic CMV infection post-HCT were …

[HTML][HTML] Valganciclovir in infants with hearing loss and clinically Inapparent congenital cytomegalovirus infection: a nonrandomized controlled trial

PK Chung, FAJ Schornagel, W Soede… - The Journal of …, 2024 - Elsevier
… The aim of the present study was to investigate whether valganciclovir treatment can
prevent deterioration of hearing in children with hearing loss and clinically inapparent cCMV. …

Treatment of cytomegalovirus anterior segment infection with intravitreal injection of ganciclovir in adjunction with or without oral valganciclovir: A long-term results

YC Cheng, EYC Kang, YS Hwang, CH Hsiao - Scientific reports, 2021 - nature.com
We evaluated the therapeutic outcome of intravitreal injection (IVI) of ganciclovir with/without
oral valganciclovir for cytomegalovirus (CMV) anterior segment infection. We enrolled 61 …

[HTML][HTML] Onset of valganciclovir resistance in two infants with congenital cytomegalovirus infection

F Garofoli, G Lombardi, M Angelini… - … Journal of Infectious …, 2020 - Elsevier
… long-term valganciclovir therapy. In the first case, valganciclovir therapy was prolonged beyond
… reduction following valganciclovir administration and no adverse events, CMV viral load …

[HTML][HTML] Management of cytomegalovirus infection in pregnancy: is it time for valacyclovir?

L Zammarchi, T Lazzarotto, M Andreoni… - … and Infection, 2020 - Elsevier
… In conclusion, the valacyclovir treatment significantly increased the portion of asymptomatic
neonates from 43%, without treatment, to 82% with treatment. There was no overlap in 95% …