Type I interferon regulates cytokine-delayed neutrophil apoptosis, reactive oxygen species production and chemokine expression

L Glennon-Alty, RJ Moots, SW Edwards… - Clinical & …, 2021 - academic.oup.com
… vivo neutrophils isolated from RA synovial fluid [19,20]. IFN-γ also delays neutrophil apoptosis
… However, the effect of type I IFNs on neutrophil function is less clear, with studies reporting …

Upregulated PD-L1 delays human neutrophil apoptosis and promotes lung injury in an experimental mouse model of sepsis

J Wang, Y Wang, J Xie, Z Zhao, S Gupta… - Blood, The Journal …, 2021 - ashpublications.org
neutrophils isolated from patients with sepsis and healthy volunteers and correlated negatively
with apoptosis rates in septic neutrophils … contributes to delayed neutrophil apoptosis, we …

The role of neutrophil death in chronic inflammation and cancer

C Brostjan, R Oehler - Cell Death Discovery, 2020 - nature.com
… can delay neutrophil apoptosis to exploit their pro-angiogenic and pro-metastatic properties.
Conversely, neutrophils … are expelled DNA strands with neutrophil proteins. Components of …

Macrophage migration inhibitory factor inhibits neutrophil apoptosis by inducing cytokine release from mononuclear cells

L Schindler, L Zwissler, C Krammer… - Journal of Leukocyte …, 2021 - academic.oup.com
… Moreover, we demonstrate that MIF proteins act synergistically together with CXCL8 to delay
neutrophil apoptosis. We also provide evidence that the chemokine receptor CXCR2 plays …

The pro-apoptotic ARTS protein induces neutrophil apoptosis, efferocytosis, and macrophage reprogramming to promote resolution of inflammation

N Maimon, ZZ Zamir, P Kalkar, O Zeytuni-Timor… - Apoptosis, 2020 - Springer
… displayed a delayed neutrophil apoptosis together with a delayed resolution of inflammation
[90]. We have yet to test whether in Sept4/ARTS −/− mice delayed apoptosis and resolution …

Cancer‐associated V‐ATPase induces delayed apoptosis of protumorigenic neutrophils

SA Ibrahim, A Kulshrestha, GK Katara… - Molecular …, 2020 - Wiley Online Library
… hand, a2NTD maintained neutrophil survival and inhibited its spontaneous apoptosis at this
time point. At the later time points, a2NTD delayed neutrophil apoptosis significantly and this …

Neutrophil and remnant clearance in immunity and inflammation

A Singhal, S Kumar - Immunology, 2022 - Wiley Online Library
… Nonetheless, inhibition of neutrophil apoptotic pathways results in increased survival …
neutrophil death [24-27]. Interestingly, the enforced Bcl-2 induced delaying of neutrophil apoptosis

Dysregulation of neutrophil death in sepsis

C Zhu, Y Wang, Q Liu, H Li, C Yu, P Li, X Deng… - Frontiers in …, 2022 - frontiersin.org
… factors appears to be the primary cause of the delayed neutrophil apoptosis (66). Although …
are essential for the delayed neutrophil apoptosis. A study on neutrophil apoptosis in patients …

[HTML][HTML] Suppressive effects of S100A8 and S100A9 on neutrophil apoptosis by cytokine release of human bronchial epithelial cells in asthma

DH Kim, A Gu, JS Lee, EJ Yang, A Kashif… - … Journal of Medical …, 2020 - ncbi.nlm.nih.gov
… Inhibition of neutrophil apoptosis prolongs the neutrophilNeutrophil apoptosis is regulated
by a variety of cytokines such as … increased cytokines delay constitutive neutrophil apoptosis. …

Manipulation of Autophagy and Apoptosis Facilitates Intracellular Survival of Staphylococcus aureus in Human Neutrophils

ME Mulcahy, EC O'Brien, KM O'Keeffe… - Frontiers in …, 2020 - frontiersin.org
… a delay in neutrophil apoptosis as well as increased expression of several anti-apoptotic
Importantly, blocking autophagy in infected PMN partially restored levels of apoptosis to that …