[HTML][HTML] Curcumin: An epigenetic regulator and its application in cancer

T Ming, Q Tao, S Tang, H Zhao, H Yang, M Liu… - Biomedicine & …, 2022 - Elsevier
… of curcumin by development of novel curcumin analogs with … for curcumin, and combination
therapy of curcumin with other … Curcumin is reportedly a potent DNA hypomethylation agent

Curcumin as an epigenetic therapeutic agent in myelodysplastic syndromes (Mds)

X Xie, D Frank, PK Patnana, J Schütte… - International Journal of …, 2021 - mdpi.com
… of myeloid and lymphoid cell lineages and was implicated in the development of … leads
to epigenetic changes in human and murine AML blasts and accelerated the development of …

Curcumin and its analogs as potential epigenetic modulators: Prevention of diabetes and its complications

C Tang, Y Liu, S Liu, C Yang, L Chen, F Tang, F Wang… - Pharmacology, 2022 - karger.com
epigenetic modulators of curcumin and analogs for prevention of metabolic diseases, and
accelerate development of … studies demonstrated that curcumin is a hypomethylation agent [37-…

Curcumin from turmeric rhizome: A potential modulator of DNA methylation machinery in breast cancer inhibition

K Fabianowska-Majewska, A Kaufman-Szymczyk… - Nutrients, 2021 - mdpi.com
… of potential epigenetic mechanisms of curcumin in reversing altered … such as curcumin to
evade the development of resistance … of curcumin as an epigenetic anti-cancer agent are new …

Polyphenols as potent epigenetics agents for cancer

P Rajendran, SA Abdelsalam, K Renu… - International journal of …, 2022 - mdpi.com
… Diverse epigenetic changes occur in cancer cells in the early stages of tumor development
[… Recent studies have shown curcumin acts as an epigenetic modulator of TREM-1 gene …

Effective role of Curcumin on expression regulation of EZH2 histone methyltransferase as a dynamic epigenetic factor in osteogenic differentiation of human …

M Ghorbaninejad, M Khademi-Shirvan… - … et Biophysica Acta (BBA …, 2023 - Elsevier
… The development of natural compounds is attracting more and more attention as … nutraceutical
agents like Curcumin would be an appealing strategy to enhance the epigenetic efficiency …

Modulation of the activity of histone lysine methyltransferases and demethylases by curcumin analog in leukaemia cells

S Sawesi, SA Malkaram… - Journal of Cellular …, 2022 - Wiley Online Library
… drawbacks that limit its development as an antitumor agent. … curcumin and DMC that support
their use and development … and curcumin decreased the methylation of the three epigenetic

Epigenetics/epigenomics and prevention by curcumin of early stages of inflammatory‐driven colon cancer

R Wu, L Wang, R Yin, R Hudlikar, S Li… - Molecular …, 2020 - Wiley Online Library
… With our increased understanding of the molecular and epigenetic/epigenomic changes
during CRC development, we will be able to develop new and more precise therapies, …

Progress and promises of epigenetic drugs and epigenetic diets in cancer prevention and therapy: A clinical update

P Mondal, J Natesh, D Penta, SM Meeran - Seminars in Cancer Biology, 2022 - Elsevier
Epigenetic modifications are heritable yet reversible, essential for normal physiological
functions and biological development. … act as chemotherapeutic and chemopreventive agents. …

Antioxidant, anti‐inflammatory and epigenetic potential of curcumin in Alzheimer's disease

T Abdul‐Rahman, WA Awuah, T Mikhailova… - …, 2024 - Wiley Online Library
Curcumin's role in attenuating the development of Aβ plaques in the brain and promoting …
Pharmacodynamics of curcumin as DNA hypomethylation agent in restoring the expression …