… behavioral and developmental gene regulation comes from evolutionary analysis. The rich
literature on evolutionary developmental biology (“evo-devo”) (16, 37) has revealed genetic “…

… In recent years, the concept of Gene Regulatory Networks (GRNs) has grown popular as
an effective applied biology approach for describing the complex and highly dynamic set of …

… (83.8%), there was a negative correlation between development and NMDA treatment,
with decreasing developmental genes, such as ascl1a, increasing in expression in …

… The interplay between chromatin, transcription factors and genes generates complex
regulatory circuits that can be represented as gene regulatory networks (GRNs). The study of …

… gene expression programmes. A deeper mechanistic understanding of the gene regulatory
networks of … developmental contexts, such as regulation of the INK4a/ARF tumour-suppressor …

… Here, we demonstrate that integrated analysis and engineering of gene regulatory networks
(GRNs) in PSC-derived multilineage human liver organoids direct maturation and vascular …

… Single-cell RNA sequencing (scRNA-seq) experiments are attractive for gene regulatory
network inference for two reasons. First, scRNA-seq experiments now routinely produce …

… A central question that arises now is whether we can discover the gene regulatory networks
(… that explore gene regulatory interactions underlying various developmental and tissue …

… Here, we present SERGIO, a simulator of single-cell gene expression data that … regulation
of genes by multiple transcription factors according to a user-provided gene regulatory network…

… gene regulatory networks often appear to be highly interconnected 26,27 , the sources of
this regulatory … are created for other species, environments and regulatory regions, our …