… affinity-based methods. We discuss examples where plasma proteomics contributed valuable
insights … offered by combining proteomics with genetic data. As a contribution to the Human …

… plasma protein levels for association with 373 diseases and other traits and identified 257,490
associations. We integrated pQTL and genetic associations with diseases … approaches for …

… biomarkers for Alzheimer's disease (AD). We systematically profiled the plasma proteome to
identify novel … using PEA technology (Supplementary Methods). The levels of the assayed …

… The need for precision medicine approaches to monitor health and disease makes it … assays
for proteome profiles in blood. Here, we describe an approach for plasma profiling based on …

… By using an unbiased proteomics approach, we show that, in both discovery and validation
cohorts, elevated baseline serum level of leukemia inhibitory factor (LIF) is associated with a …

… or plasma EGC screening methods, and novel biomarkers need to be explored. The development
of plasma proteomics … plasma with a proteomic method to discover novel biomarkers. …

… interpretable method to study organ aging using plasma proteomics data, predicting diseases
… present one of the largest studies of plasma proteome aging to date, but as larger plasma …

… ’s disease and dementia more broadly 1,2,3,4 , information about the full range of changes to
the plasma proteome … ‘omics’ approach to understanding the plasma proteomic differences …

… We use three methods to establish such a relationship: high LD (r 2 > 0.8) between a pQTL
and a disease-associated variant, inclusion of a disease-associated variant in the subset of …

… the disease. Using label-free quantitative proteomics, we performed deep plasma proteome
… 33 severe) to understand the disease dynamics. Of the 1200 proteins detected in the patient …