Solubility Enhancement of Glipizide and Development of its Fast-dissolving Oral Film

HA Pawar, MSMA Momin - Current Drug Therapy, 2021 - ingentaconnect.com
… dispersion of the glipizide showed improved solubility by almost 10 folds. Many of the formulated
films … Conclusion: The solubility of Glipizide was improved successfully by solubilization …

[HTML][HTML] Formulation and characterization of glipizide solid dosage form with enhanced solubility

BS Alotaibi, MA Khan, K Ullah, H Yasin, A Mannan… - Plos one, 2024 - journals.plos.org
… The primary aim of this study was to explore the potential for enhancing the solubility and
dissolution rate of glipizide solid dosage form. This was achieved by creating solid dispersions …

Formulation, characterization, and pharmacokinetic evaluation of novel glipizide-phospholipid nano-complexes with improved solubility and bio-availability

S Rathor, DC Bhatt - Pharmaceutical Nanotechnology, 2022 - ingentaconnect.com
… of the dissolving media significantly impacts glipizide dissolution, … pH, glipizide is a fundamental
molecule with enhanced solubility. … , the compound improved solubility and dissolution. …

Solubility measurement and various solubility parameters of glipizide in different neat solvents

MA Kalam, A Alshamsan, M Alkholief, IA Alsarra… - ACS …, 2020 - ACS Publications
… , increasing the solubility is an essential criterion for its enhanced bioavailability. The
solubility, dissolution, and eventually the bioavailability of GLZ can be improved by different …

Formulation and Evaluation of Glipizide Fast Dissolving Tablets

S Swati, RLS Suma, SN Prasanna… - Journal of …, 2020 - search.proquest.com
… This study shows that the disintegration and dissolution rate of Glipizide FDT enhanced to a
greater … of Glipizide for solubility and dissolution rate enhancement. IJPDA. 2014 Feb; 2(2). …

[PDF][PDF] ENHANCEMENT OF SOLUBILITY AND DISSOLUTION RATE OF GLIPIZIDE BY LIQUISOLID TECHNIQUE

IS Raj, RN Babu, I Sirisha, Y Sushmitha, M Sirisha - jcdronline.org
… flowing powder with enhanced dissolution rate. In the present study, Liqui-solid compacts is
applied to enhance the dissolution of the Glipizide Twenty two formulations of Glipizide were …

[PDF][PDF] DESIGN AND IN-VITRO EVALUATION OF INCLUSION COMPLEX OF WATER INSOLUBLE DRUG GLIPIZIDE

RA Khan, MM Iqbal, MA ur Rehman, A Khan - 2023 - wjpr.s3.ap-south-1.amazonaws.com
… increase the dissolution and bioavailability of poorly water-soluble drugs… solubility and
dissolution rate of Glipizide by solid dispersions (SDs) and investigate them for in vitro dissolution

[HTML][HTML] Formulation and evaluation of stabilized glipizide nanosuspension prepared by precipitation method

MS Raja, K Venkataramana - Evaluation, 2020 - rjptonline.org
Glipizide is a BCS Class II drug which shows low solubility and high permeability 11-15 . The
nanosuspension approach is widely used to overcome the issues of solubilitydissolution

Hydroxyl-terminated triazine dendrimers mediated pH-dependent solubility enhancement of glipizide across dendritic generations: A comparative investigation

MH Malek - The Scientific Temper, 2024 - scientifictemper.com
… A stimulating tale of solubility improvement emerged from our research. Glipizide’s solubility
was … The solubility of hydrophobic drugs in water can be dramatically altered by dendrimers …

In vivo evaluation of solid dispersion of glipizide with low viscosity grade hydroxypropyl methylcellulose

S Mallick, AK Mahapatra, PN Murthy… - Research Journal of …, 2023 - indianjournals.com
Increased solubility may be due to the improved dissolution of glipizide particles in aqueous
solution … The solubility and dissolution rate of glipizide was enhanced by the use of SDs of …