The role of functional excipients in solid oral dosage forms to overcome poor drug dissolution and bioavailability

J Van der Merwe, J Steenekamp, D Steyn, J Hamman - Pharmaceutics, 2020 - mdpi.com
… Formulating a solid oral dosage form with an aqueous soluble diluent that attracts water
towards the dosage form may contribute to enhanced dissolution rate of hydrophobic/poorly …

Overview of nanoparticulate strategies for solubility enhancement of poorly soluble drugs

KU Khan, MU Minhas, SF Badshah, M Suhail, A Ahmad… - Life Sciences, 2022 - Elsevier
… Micronization technique increases the dissolution rate of poorly soluble drugs and is done …
The micronization technique has been employed for enhancing dissolution rate and solubility …

[HTML][HTML] A review on solid dispersion and carriers used therein for solubility enhancement of poorly water soluble drugs

AR Tekade, JN Yadav - Advanced pharmaceutical bulletin, 2020 - ncbi.nlm.nih.gov
enhancement of dissolution rate of drug. At the stage of supersaturation decrease in dissolution
rate … Furthermore in such system parachute like effect is observed on dissolution profile …

Elemental dissolution characteristics of granite and gabbro under high-temperature water-rock interactions

S Zhou, Q Sun, H Zhang, H Meng, Q Gao… - Science of The Total …, 2023 - Elsevier
dissolution rate. Si was the primary solute in the solution, mainly resulting from the dissolution
of quartz, and the dissolution rates … –180 C, and the dissolution rate of Si reached its peak …

Bioavailability enhancement techniques for poorly aqueous soluble drugs and therapeutics

DV Bhalani, B Nutan, A Kumar, AK Singh Chandel - Biomedicines, 2022 - mdpi.com
… The low dissolution rate and low solubility in the aqueous gastrointestinal fluids lead to … ,
bioavailability can be improved through enhancing the dissolution rate and solubility of the drug …

Development of fertilizers for enhanced nitrogen use efficiency–Trends and perspectives

CO Dimkpa, J Fugice, U Singh, TD Lewis - Science of the Total …, 2020 - Elsevier
… By adjusting temperatures and advising additional coating ingredients to the production
process, Blouin's final fertilizer granule demonstrated a 2% dissolution rate in a 24-hour (h) …

Localized Ostwald Ripening Guided Dissolution/Regrowth to Ancient Chinese Coin‐shaped VO2 Nanoplates with Enhanced Mass Transfer for Zinc Ion Storage

Z Cao, L Wang, H Zhang, X Zhang… - Advanced Functional …, 2020 - Wiley Online Library
… Motivated by these considerations, in this work, based on the localized Ostwald ripening
guided dissolution-regrowth process, the highly uniform and dispersed round VO 2 nanoplates …

Potential for large-scale CO2 removal via enhanced rock weathering with croplands

DJ Beerling, EP Kantzas, MR Lomas, P Wade… - Nature, 2020 - nature.com
dissolution within the soil profile (Supplementary Methods). The model accounts for … dissolution
rates with soil depth and time as grains dissolve, and chemical inhibition of dissolution as …

… hydrogels based on carboxymethyl chitosan and oxidized hyaluronic acid containing tanshinone extract nanocrystals for enhanced dissolution and acne treatment

X Tang, Y Liu, H Yuan, R Gao - Pharmaceuticals, 2022 - mdpi.com
… The smaller size and larger surface area of nanocrystals lead to higher dissolution rate,
hence … Moreover, the increased dissolution rate and saturation solubility intensifies the …

[HTML][HTML] Liposomes for enhanced bioavailability of water-insoluble drugs: In vivo evidence and recent approaches

MK Lee - Pharmaceutics, 2020 - mdpi.com
… to formulate because of its lipophilic nature and dissolution rate-limited absorption. There
have … The co-precipitate significantly increased the dissolution rate of carbamazepine in water …