[HTML][HTML] … supplementation alleviates reduced ureteric branching, nephrogenesis, and global DNA methylation induced by maternal nutrient restriction in rat embryonic …

M Awazu, M Hida - PloS one, 2020 - journals.plos.org
DNA methylation of various organs including the kidney [7]. DNA methylation is regulated
by DNA … folic acid supplementation on global DNA methylation of rat E18 embryonic kidney. …

[HTML][HTML] Differences in DNA methylation reprogramming underlie the sexual dimorphism of behavioral disorder caused by prenatal stress in rats

L Lei, X Wu, H Gu, M Ji, J Yang - Frontiers in Neuroscience, 2020 - frontiersin.org
… induces a stress response in dams that has a negative effect on the viability of rat
embryos. … deficits in female but not male rats exposed to PS might be DNA methylation-dependent. …

Choline acts during preimplantation development of the bovine embryo to program postnatal growth and alter muscle DNA methylation

E Estrada-Cortés, W Ortiz, MB Rabaglino, J Block… - FASEB Journal, 2021 - orbit.dtu.dk
… Several histone modifications near IGF1 caused by intrauterine growth retardation in rats
and DNA methylation in cultured blastocysts.In the present study, the bovine embryo produced …

[HTML][HTML] Maternal folic acid impacts DNA methylation profile in male rat offspring implicated in neurodevelopment and learning/memory abilities

X Wang, Z Li, Y Zhu, J Yan, H Liu, G Huang, W Li - Genes & nutrition, 2021 - Springer
… for numerous methylation reactions, including DNA methylation [8]. DNA methylation and …
epigenetic modifications reprogrammed considerably in early embryonic development [9]. …

[HTML][HTML] N6-Methyladenine in Eukaryotic DNA: Tissue Distribution, Early Embryo Development, and Neuronal Toxicity

SB Fernandes, N Grova, S Roth, RC Duca… - Frontiers in …, 2021 - frontiersin.org
… states that DNA methylation in eukaryotes … rats exposed to the higher level of the pollutant
(66 ng/kg/day). These observations are in line with the observed changes in DNA methylation (…

Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis

L Ma, Q Tang, X Gao, J Lee, R Lei, M Suzuki… - Science …, 2022 - science.org
… , complete loss of Tet1/2/3 mRNA, and depletion of 5hmC in Tet1/2/3 f/f ;R26 +/CreER
embryos using DNA and RNA isolated from whole embryos (fig. S1, C to E). We analyzed the …

[HTML][HTML] High-fat diet-induced and genetically inherited obesity differentially alters DNA methylation profile in the germline of adult male rats

SS Deshpande, H Nemani, G Arumugam… - Clinical …, 2020 - Springer
… The present study aimed to understand the effect of DIO and GIO on DNA methylation in …
(post-implantation embryo loss) and normal embryos. First, we assessed the DNA methylation

[HTML][HTML] … in one-carbon metabolism within the ovarian follicle, oocyte, and preimplantation embryo: consequences for epigenetic programming of DNA methylation

CE Clare, V Pestinger, WY Kwong, DAR Tutt… - International Journal of …, 2021 - mdpi.com
One-carbon (1C) metabolism provides methyl groups for the synthesis and/or methylation of
purines and pyrimidines, biogenic amines, proteins, and phospholipids. Our understanding …

[HTML][HTML] Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals

CB Mulholland, A Nishiyama, J Ryan… - Nature …, 2020 - nature.com
… of inducing global DNA demethylation in non-… embryonic stem cells (ESCs) cultured in
conditions promoting naïve pluripotency 49,50,51 as a model to study global DNA demethylation

[HTML][HTML] In utero exposure to gestational diabetes alters DNA methylation and gene expression of CDKN2A/B in langerhans islets of rat offspring

Z Nazari, A Shahryari, S Ghafari, M Nabiuni… - Cell Journal …, 2020 - ncbi.nlm.nih.gov
… In this experimental study, we delineated DNA methylation … -old rat offspring of
streptozotocin-induced GDM dams. We performed bisulfite sequencing to determine the DNA