DNA methylation-linked chromatin accessibility affects genomic architecture in Arabidopsis

Z Zhong, S Feng, SH Duttke… - Proceedings of the …, 2021 - National Acad Sciences
DNA methylation and chromatin accessibility, we performed assay for transposase-accessible
chromatin … show that chromatin accessibility anticorrelates with DNA methylation, as has …

[HTML][HTML] DNA methylation: Precise modulation of chromatin structure and dynamics

S Li, Y Peng, AR Panchenko - Current opinion in structural biology, 2022 - Elsevier
… structure include using murine DNA methyltransferases in budding yeast which … lack DNA
methylation machinery [8∗∗]. This approach found that DNA methylation resulted in chromatin

Impact of DNA methylation on 3D genome structure

D Buitrago, M Labrador, JP Arcon, R Lema… - Nature …, 2021 - nature.com
… changes in global chromatin structure with a noticeable increase in gene condensation.
Overall, our results demonstrate that DNA methylation affects chromatin structure and function …

[HTML][HTML] The regulatory function of piRNA/PIWI complex in cancer and other human diseases: The role of DNA methylation

DD Jia, H Jiang, YF Zhang, Y Zhang… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
… changes represented by DNA methylation and chromatin modification. … DNA methylation
regulation mechanisms and methylation … Since DNA methylation and inhibitory chromatin marks …

Dual detection of chromatin accessibility and DNA methylation using ATAC-Me

LN Guerin, KR Barnett, E Hodges - Nature protocols, 2021 - nature.com
… ATAC-Me is an integrated method to probe DNA methylation and chromatin accessibility
from a single DNA fragment library. Intact nuclei undergo Tn5 transposition to isolate …

[HTML][HTML] Large DNA methylation nadirs anchor chromatin loops maintaining hematopoietic stem cell identity

X Zhang, M Jeong, X Huang, XQ Wang, X Wang… - Molecular cell, 2020 - cell.com
… Higher-order chromatin structure and DNA methylation are … Here, we find that large (>7.3
kb) DNA methylation nadirs (… -marked large DNA methylation grand canyons represent a …

Inference of emergent spatio-temporal processes from single-cell sequencing reveals feedback between de novo DNA methylation and chromatin condensates

F Olmeda, T Lohoff, SJ Clark, L Benson, F Krüger… - bioRxiv, 2021 - biorxiv.org
… and global de novo methylation of the genome. We show how DNA methylation patterns of
the … between spatially correlated DNA methylation and topological changes to the DNA. This …

Changes in DNA methylation hallmark alterations in chromatin accessibility and gene expression for eye lens differentiation

J Disatham, L Brennan, X Jiao, Z Ma… - … & Chromatin, 2022 - Springer
… their DNA binding affinities [8, 14,15,16,17,18] to modulate gene expression. Consistent with
these properties, DNA methylation … role of DNA methylation on the modulation of chromatin

The interplay between DNA and histone methylation: molecular mechanisms and disease implications

Y Li, X Chen, C Lu - EMBO reports, 2021 - embopress.org
… A central question in the field is how DNA methylation machineries interact with other
chromatin components to ensure faithful establishment and maintenance of genome‐wide CpG …

Active turnover of DNA methylation during cell fate decisions

A Parry, S Rulands, W Reik - Nature Reviews Genetics, 2021 - nature.com
… Ectopic expression of the Yamanaka factors is sufficient to convert somatic cells into iPSCs
81 , and during this process the condensed and highly methylated chromatin of somatic cells …