DNA methylation biomarkers of future health outcomes in children

S Shanthikumar, MR Neeland, J Maksimovic… - Molecular and Cellular …, 2020 - Springer
… , treatment response, or development of complications. Studies … which attempt to link DNA
methylation to current disease state … of DNA methylation profiles in development of disease. …

Structural basis for impairment of DNA methylation by the DNMT3A R882H mutation

H Anteneh, J Fang, J Song - Nature communications, 2020 - nature.com
… of mammalian DNA methylation during development. The R882H DNMT3A is a hotspot
mutation in acute myeloid leukemia (AML) causing aberrant DNA methylation. However, how …

Transgenerational sperm DMRs escape DNA methylation erasure during embryonic development and epigenetic inheritance

M Ben Maamar, Y Wang, EE Nilsson… - Environmental …, 2023 - academic.oup.com
… a DNA methylation imprint that escapes the DNA methylation erasure for the morula embryo,
several paternal and maternal imprinted sites were evaluated to assess DNA methylation

[HTML][HTML] DNA Methylation of Postnatal Liver Development in Pigs

Y Wang, H Jin, X Tong, H Yu, X Li, B Zeng - Genes, 2024 - mdpi.com
… (LPIN1 and ACOX2), lost DNA methylation in their promoter, with mRNA expression increased
… of genome-wide DNA methylation patterns in pig liver postnatal development and growth. …

QSER1 protects DNA methylation valleys from de novo methylation

G Dixon, H Pan, D Yang, BP Rosen, T Jashari… - Science, 2021 - science.org
… Creation of a knockin DNA methylation reporter line … DNA methylation at regions with
similar chromatin features, which would inform not only gene regulation during development but …

DNA methylation changes induced by BDE-209 are related to DNA damage response and germ cell development in GC-2spd

X Li, Y Zhang, X Dong, G Zhou, Y Sang, L Gao… - Journal of …, 2021 - Elsevier
… But it still remains unclear about the effects of BDE-209 on DNA methylation and the … line
development, we hypothesize that BDE-209 exposure impacts the statue of DNA methylation in …

Are alterations in DNA methylation related to CKD development?

J Rysz, B Franczyk, M Rysz-Górzyńska… - International Journal of …, 2022 - mdpi.com
DNA methylation can modulate the expression of pro-inflammatory and pro-fibrotic genes, as
well those essential for kidney development … variations in DNA methylation and fibrosis and …

DNA methylation age acceleration contributes to the development and prediction of non-alcoholic fatty liver disease

M Xia, W Li, H Lin, H Zeng, S Ma, Q Wu, H Ma, X Li… - GeroScience, 2024 - Springer
DNA methylation age acceleration, a hallmark of aging, with risk of NAFLD. Genome-wide
DNA methylationDNA methylation age was calculated using the Horvath’s method, and liver …

Dynamics of DNA hydroxymethylation and methylation during mouse embryonic and germline development

R Yan, X Cheng, C Gu, Y Xu, X Long, J Zhai, F Sun… - Nature Genetics, 2023 - nature.com
DNA methylation in mouse zygotes remains debatable 9 . Moreover, although a small repertoire
of maternal genes are known to affect DNA methylation … in methylation reprogramming …

Discovering DNA methylation, the history and future of the writing on DNA

JD Tompkins - Journal of the History of Biology, 2022 - Springer
… differentiation in development, it is reflected in DNA presentation: chemical decorations, …
In the ensuing pages, I will predominately describe DNA methylation (DNAme) as it is …