DNA methylation dynamics during germline development

S He, X Feng - Journal of Integrative Plant Biology, 2022 - Wiley Online Library
… In animals, DNA methylation is also developmentally … the understanding that DNA methylation
plays a similar role in … dynamic changes in DNA methylation during germline development. …

DNA methylation dynamics in the female germline and maternal-effect mutations that disrupt genomic imprinting

Z Anvar, I Chakchouk, H Demond, M Sharif, G Kelsey… - Genes, 2021 - mdpi.com
… key milestones in DNA methylation patterning in the female germline and the embryo focusing
on humans. We provide an overview of recent findings regarding DNA methylation deficits …

The impact of DNA methylation dynamics on the mutation rate during human germline development

Y Zhou, F He, W Pu, X Gu, J Wang… - G3: Genes, Genomes …, 2020 - academic.oup.com
… Our study provides evidence that DNA methylation in germline relevant cells has a … DNA
methylation levels mentioned in this study are specifically referred to as the DNA methylation

DNA methylation reprogramming of genomic imprints in the mammalian germline: A TET‐centric view

BA Caldwell, MS Bartolomei - Andrology, 2023 - Wiley Online Library
… that are critical to achieving a DNA hypomethylated state, with … DNA methylation dynamics
in the mammalian genome, with a particular emphasis on DNA demethylation in the germline

Repression of germline genes by PRC1. 6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing

K Mochizuki, J Sharif, K Shirane, K Uranishi… - Nature …, 2021 - nature.com
Silencing of a subset of germline genes is dependent upon DNA methylation (DNAme) post-implantation.
However, these genes are generally hypomethylated in the blastocyst, …

Genome-wide DNA methylation dynamics during epigenetic reprogramming in the porcine germline

I Gómez-Redondo, B Planells, S Cánovas, E Ivanova… - Clinical …, 2021 - Springer
DNA methylation, as evaluated from the median methylation of … Given that the methylation
level in somatic cells of the pig fetus … b PCA of DNA methylation of tiles of 100 CpG sites of the …

High-fat diet-induced and genetically inherited obesity differentially alters DNA methylation profile in the germline of adult male rats

SS Deshpande, H Nemani, G Arumugam… - Clinical …, 2020 - Springer
… To study the effect of high-fat diet-induced and genetically inherited obesity on DNA methylation
in the male germline, we first assessed the DNA methyltransferases expression pattern …

Metabolic liver cancer: associations of rare and common germline variants in one-carbon metabolism and DNA methylation genes

SO Antwi, M Heckman, L White, I Yan… - Human molecular …, 2023 - academic.oup.com
… is also implicated in DNA methylation through the production … that is used for DNA methylation
(covalent attachment of a … one-carbon metabolism and DNA methylation, it is important …

Comparison of RNA m6A and DNA methylation profiles between mouse female germline stem cells and STO cells

X Zhao, GG Tian, Q Fang, X Pei, Z Wang… - Molecular Therapy-Nucleic …, 2021 - cell.com
… female germline stem cells (mFGSCs) have been published. In this study, we compared the
genome-wide profiles of mRNA m 6 A methylation and DNA methylation … of methylated DNA

Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity

T Dahlet, A Argüeso Lleida, H Al Adhami… - Nature …, 2020 - nature.com
… panel of germline genes. While we and others previously found some germline genes reactivated
… that the set of germline genes repressed by CpG-island DNA methylation is larger than …