DNA methylation profiling: an emerging paradigm for cancer diagnosis

A Papanicolau-Sengos, K Aldape - Annual Review of Pathology …, 2022 - annualreviews.org
DNA methylation profiling is an additional emerging tool that … Tumor DNA methylation profiling
has led to the identification … In addition, DNA methylation patterns in circulating tumor DNA

Sarcoma classification by DNA methylation profiling

C Koelsche, D Schrimpf, D Stichel, M Sill… - Nature …, 2021 - nature.com
… We here describe a high stability of methylation profiles for sarcoma entities. In addition, our
… A practical example for the high stability of methylation profiles established by this approach …

DNA methylation profiling of human hepatocarcinogenesis

G Hernandez‐Meza, J von Felden… - …, 2021 - Wiley Online Library
… (10) In total, this study analyzed DNA methylation profiles of 390 tissue samples (246
previously reported(10) and 144 newly analyzed for this study) from a total of 248 patients (Fig. 1). …

Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19

MJ Corley, APS Pang, K Dody, PA Mudd… - Journal of leukocyte …, 2021 - academic.oup.com
DNA methylation signature associated with severe COVID-19. (A) Overview of experimental
… comparative DNA methylation profiling. (B) Box and whisker plots of DNA methylation cell …

Genetic alteration, RNA expression, and DNA methylation profiling of coronavirus disease 2019 (COVID-19) receptor ACE2 in malignancies: a pan-cancer analysis

P Chai, J Yu, S Ge, R Jia, X Fan - Journal of hematology & oncology, 2020 - Springer
… not compare global DNA methylation level of KICH. Instead, we compared DNA methylation
level of KICH across different tumor stages, and we found that the DNA methylation was not …

A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR

P Sievers, M Sill, D Schrimpf, D Stichel… - Neuro …, 2021 - academic.oup.com
… genetic alterations and DNA methylation profiles such as … appeared to share a unique DNA
methylation pattern and global loss … of genome-wide DNA methylation profiling data of these …

Aberrant DNA methylation profile exacerbates inflammation and neurodegeneration in multiple sclerosis patients

N Celarain, J Tomas-Roig - Journal of neuroinflammation, 2020 - Springer
… altering the DNA sequence. The most studied epigenetic mechanism is DNA methylation.
This … In conclusion, an exhaustive study of DNA methylation might contribute towards new …

DNA methylation methods: Global DNA methylation and methylomic analyses

S Li, TO Tollefsbol - Methods, 2021 - Elsevier
… current and emerging DNA methylation and … DNA methylation profiling techniques. These
approaches hold promise for facilitating our comprehensive understanding of DNA methylation

Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1

P Sievers, M Sill, C Blume, A Tauziede-Espariat… - Acta …, 2021 - Springer
… Genomic DNA was extracted from formalin-fixed and paraffin-embedded (FFPE) tissue
samples. DNA methylation profiling of all samples was performed using the Infinium …

Analysis of DNA methylation profiles during sheep skeletal muscle development using whole-genome bisulfite sequencing

Y Fan, Y Liang, K Deng, Z Zhang, G Zhang, Y Zhang… - BMC genomics, 2020 - Springer
… However, DNA methylation regulators involved in sheep … DNA methylation during sheep
muscle growth, this study systematically investigated the genome-wide DNA methylation profiles