[HTML][HTML] Exosome-inflammasome crosstalk and their roles in inflammatory responses

C Noonin, V Thongboonkerd - Theranostics, 2021 - ncbi.nlm.nih.gov
… and their roles in inflammatory responses. The effects of inflammasome activation on
exosomal secretion are summarized. On the other hand, the (dual) effects of exosomes on …

[HTML][HTML] Modulation of the inflammatory response and bone healing

M Maruyama, C Rhee, T Utsunomiya… - Frontiers in …, 2020 - frontiersin.org
… switch of expression patterns from a pro-inflammatory to an anti-inflammatory response (IL4,
IL10, IL13) in the late stages of inflammation is critical to fracture repair. Inflammatory Phase …

[HTML][HTML] Dual effect of immune cells within tumour microenvironment: pro-and anti-tumour effects and their triggers

AC Peña-Romero, E Orenes-Piñero - Cancers, 2022 - mdpi.com
… of vital importance in sustaining an immune response during certain inflammatory conditions
(their recruitment enhances TNF and iNOS-producing inflammatory DCs). Despite the fact …

[HTML][HTML] Dual nature of type I interferons in SARS-CoV-2-induced inflammation

C King, J Sprent - Trends in immunology, 2021 - cell.com
… and for effective antiviral immune responses; for this reason, … immune response and
exacerbate inflammatory disease at … -2 shape the immune response and whether this might be …

Mesenchymal stromal cells in cancer: a review of their immunomodulatory functions and dual effects on tumor progression

S Galland, I Stamenkovic - The Journal of pathology, 2020 - Wiley Online Library
… In the context of tissue injury, MSCs can respectively promote and attenuate inflammation
of the inflammatory response and secrete mediators that boost or temper the response as …

[HTML][HTML] A COX-2/sEH dual inhibitor PTUPB alleviates lipopolysaccharide-induced acute lung injury in mice by inhibiting NLRP3 inflammasome activation

HH Yang, JX Duan, SK Liu, JB Xiong, XX Guan… - Theranostics, 2020 - ncbi.nlm.nih.gov
… We evaluated the effects of PTUPB on the inflammatory response of primary murine
macrophages and found that low-dose PTUPB (≤1000 nM) had no detectable influence on LDH …

[HTML][HTML] NLRP3 inflammasome regulates development of systemic inflammatory response and compensatory anti-inflammatory response syndromes in mice with …

M Sendler, C van den Brandt, J Glaubitz, A Wilden… - Gastroenterology, 2020 - Elsevier
… we found systemic inflammatory response syndrome and compensatory anti-inflammatory
response syndrome developed in parallel. Infiltrating macrophages promote inflammation and …

[HTML][HTML] The dual role of platelet‐innate immune cell interactions in thrombo‐inflammation

J Rayes, JH Bourne, A Brill, SP Watson - Research and practice in …, 2020 - Elsevier
… platelets and innate immune cells and their dual role in the regulation of the inflammatory
response in sterile and infectious thrombo‐inflammatory diseases. A better understanding of …

Anti‐inflammatory Effects of Empagliflozin and Gemigliptin on LPS‐Stimulated Macrophage via the IKK/NF‐κB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways

N Lee, YJ Heo, SE Choi, JY Jeon… - Journal of …, 2021 - Wiley Online Library
… anti-inflammatory properties that can be mediated by directly or indirectly regulating the
inflammatory response, and … We clarified for the first time that the dual therapy, empagliflozin and …

Dual-omics reveals temporal differences in acute sympathetic stress-induced cardiac inflammation following α1 and β-adrenergic receptors activation

D Zhang, M Zhao, J Wu, R Wang, G Xue… - Acta Pharmacologica …, 2023 - nature.com
… To obtain temporal profiles of the inflammatory responses, we separated mouse heart tissues
at time points of 1 h and 1 day after β-AR agonist (Isoproterenol, ISO) and α 1 -AR agonist (…